This collection includes theses and dissertations from the Department of Microbiology and Immunology, in the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please see: http://ir.library.louisville.edu/about.html.

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Theses/Dissertations from 2016

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SA-4-1BBL as a modulator of innate, adaptive, and regulatory immunity : implications for cancer prevention and treatment., Hampartsoum Barsoumian

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Identification of host factors required for Yersinia pestis macrophage intracellular survival and their impact on vacuole maturation, acidification and trafficking., Michael Graylin Connor

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Impact of epigallocatechin-3-gallate (EGCG), a broad-spectrum anti-inflammatory, in controlling intestinal factors contributing to inflammatory bowel disease., Gerald Wayne Dryden, Jr.

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Microbiota activated CD103+ DCS stemming from oral microbiota adaptation specifically drive γδT17 proliferation and activation., Christopher Jay Fleming

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In vivo monitoring of therapeutic efficacy and virulence profile by bioluminescent Klebsiella pneumoniae., Ramy Ameen Fodah

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Characterization of the role of the Burkholderia pseudomallei type 3 secretion system using in vivo imaging., Maria Gabriela Gutierrez

Theses/Dissertations from 2015

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Immunomodulation of myeloid-derived suppressor cells by particulate b-glucan in cancer., Sabrin Husein Albeituni

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Critical insights into the pathogenesis of clinical isolates of pandemic influenza A(H1N1) 2009 virus in mouse and ferret models., Jeremy V. Camp 1980-

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Chemoattractant receptors BLT1 and CXCR3 regulate anti-tumor immunity by facilitating CD8+ T cell migration to tumors., Zinal S. Chheda

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Early host response and immune signaling to 2009 pandemic influenza A (H1N1) viruses in primary cell culture models., Rachael Lask Gerlach

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Characterization of the innate response to the RagB protein of Porphyromonas gingivalis., Justin Hutcherson

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Functional characterization of Aggregatibacter actinomycetemcomitans QSEBC : a bacterial adrengeric receptor and global regulator of virulence., Whitney Weigel

Theses/Dissertations from 2014

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Modulation of host polyubiquitination by the ankb f-box protein of Legionella pneumophila., William M. Bruckert

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SA-4-1BBL as a platform to develop adjuvant systems for prophylactic and therapeutic vaccines., Gunes Dinc 1984-

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A mechanism for trif adaptor-biased signaling by toll-like receptor 4., Joseph Peterson Kolb

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IL-12 induced modulation of tumor derived myeloid cell inflammatory responsiveness., Courtney Jetun Mitchell

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Modulation of the ovarian cancer humoral response by tumor-derived exosomes., Carolyn Denise Roberson

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Regulation of macrophage inflammatory signaling pathways by AMP-activated protein kinase., Yanfang Zhu

Theses/Dissertations from 2013

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Mast cell-T cell interactions in inflammatory chemokine mediated immune surveillance of intestinal cancer., Sobha R. Bodduluri

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AMP-activated protein kinase regulation of myeloid antigen presenting cell activity., Kelly Casey Carroll

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The involvement of beta-catenin in the inflammatory response leading to autoimmune diabetes development., Arin Lee Zirnheld

Theses/Dissertations from 2012

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Blockade of CXCR4 inhibits Porphyromonas gingivalis colonization in vivo and subsequent periodontal bone loss., Megan L. Mc Intosh

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Expression of adipocyte/macrophage fatty acid binding protein promotes tumor growth and metastasis., Ashley Simone Triplett

Theses/Dissertations from 2011

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Identification and biochemical characterization of the CHLAMYDIA TRACHOMATIS type III secretion chaperone, SLC1, and its role in the translocation of the invasion-associated effector TARP., Amanda J. Brinkworth

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Reconciliation of IL-1ß loss with TRIF-biased TLR4 signaling by monophosphate lipid A., Chelsea A. Embry

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Age-associated changes in innate immunity and their impacts on inflammatory disease., Mehmet Akif Eskan

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Effect of complement C5a in tumor progression and the local tumor microenvironment., Lacey Jo Gunn

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Characterization of the AI-2-dependent quorum sensing pathway in Aggregatibacter actinomycetemcomitans., Elizabeth A. Novak

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Exploitation of costimulatory SA-4-1BBL in the development of therapeutic cancer vaccines., Abhishek K. Srivastava

Theses/Dissertations from 2010

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Tobacco-induced changes to Porphyromonas gingivalis gene expression, phenotype and host-pathogen interactions., Juhi Bagaitkar

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'Complementary' immune evasion by oral pathogen Porphyromonas gingivalis., Jennifer Lynn Krauss

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SA-4-1BBL as a modulator of T effector to T regulatory cell conversion., Shravan Madireddi 1980-

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A role for regulatory T cells in gender-biased disease susceptibility to murine lupus., Colleen Tucker

Theses/Dissertations from 2009

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The role of glycogen synthase kinase 3-beta in interferon beta biology., Huizhi Wang 1975-

Theses/Dissertations from 2007

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Non-redundant and critical roles for leukotriene B4 receptors BLT1 and BLT2 in mouse models of inflammatory arthritis., Steven Mathis 1979-

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Therapeutic targeting of tumor associated macrophages., Stephanie Kaye Watkins 1981-

Theses/Dissertations from 2006

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Molecular pathogenesis of Legionella longbeachae., Rexford Asare 1972-

Theses/Dissertations from 2005

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Sex-based differences in regulatory T cells., Lum Doreen Nebane-Ambe 1975-

Theses/Dissertations from 2002

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Structure-function studies of the vaccinia virus complement control protein., Scott Alan Smith

Theses/Dissertations from 1932

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The cause of vascular sclerosis in essential hypertension and related phenomena, Claude W. Chappell