Date on Master's Thesis/Doctoral Dissertation

8-2019

Document Type

Master's Thesis

Degree Name

M.S.

Department

Epidemiology and Population Health

Degree Program

Epidemiology, MSE

Committee Chair

Taylor, Kira

Committee Co-Chair (if applicable)

Wallis, Anne

Committee Member

Wallis, Anne

Committee Member

Gaskins, Jeremy

Author's Keywords

Female fertility; spontaneous conception; infertility; sexually transmitted infection; probability; reproductive epidemiology

Abstract

This study interrogated predictors of pregnancy and the effect of a history of sexually transmitted infection (STI) on probability of conception among a cohort of women seeking fertility counseling (N=170), using multivariable logistic regression and Cox proportional hazards models. There were 76 (44.7%) total pregnancies. 32 (39.0%) were achieved spontaneously by women who never received ART (N=82). Among women who did receive ART (N=88), 35 (39.7%) were achieved by ART and 9 (10.2%) achieved spontaneously. Among the full cohort (N=170), obesity was a significant negative predictor of pregnancy while history of human papilloma virus was a significant negative predictor of time to pregnancy. Among those who did receive ART (N=88), ovarian infertility diagnosis was a significant positive predictor of pregnancy, relative to other infertility diagnoses. History of STI was nonsignificantly associated with increased probability of pregnancy in all sub-samples, though this result may be confounded by characteristics like coital frequency.

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Epidemiology Commons

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