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The University of Louisville Journal of Respiratory Infections

11.0613

Abstract

Background: Stroke is one of the most prevalent neurological diseases in the United States. Community-acquired pneumonia (CAP) is the leading cause of infections in survivors of stroke. There is limited research evaluating the clinical outcomes of CAP in patients with stroke. The objective of this study was to evaluate the clinical characteristics and outcomes of hospitalized patients with CAP and a history of stroke.

Methods: This was a secondary analysis of the University of Louisville Pneumonia Study database. Patients were divided into two groups based on the presence or absence of a history of stroke. Clinical outcomes were length of stay, time to clinical stability, and one-year mortality, which were assessed via stratified Cox proportional hazards regression. Differences in risk of clinical outcomes were reported as adjusted hazard ratios.

Results: We found no significant differences in time to clinical stability between the two groups. The median length of stay for patients with a history of stroke hospitalized with CAP was six days and for patients without stroke was five days (P=0.01). We observed a 16% higher risk of mortality in stroke patients with CAP than in the non-stroke population (P=0.001).

Conclusions: This study indicates that hospitalized patients with CAP have a longer hospital stay and higher mortality than those without stroke.

Funder

None

DOI

10.18297/jri/vol6/iss1/4

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Table 1 Final.docx (16 kB)
Table 1 Final.docx

1. TCS.pdf (4 kB)
1. TCS.pdf

2. LOS.pdf (4 kB)
2. LOS.pdf

3. MOR_full.pdf (7 kB)
3. MOR_full.pdf

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