This collection includes theses and dissertations from the Department of Physiology and Biophysics, in the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please see: http://ir.library.louisville.edu/about.html.

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Theses/Dissertations from 2017

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Enhancing cell therapy for ischemic cardiomyopathy., Michael J. Book

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Stretching adversely modulates locomotor capacity following spinal cord injury via activation of nociceptive afferents., Anastasia V. Keller

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Mitochondrial Transcription Factor A's role in heart failure., George H. Kunkel

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Trunk and respiratory motor control in typically developing children and its implications in children with chronic spinal cord injury., Goutam Singh

Theses/Dissertations from 2016

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Cardiovascular and hematopoietic responses to volatile benzene exposure., Wesley Tyler Abplanalp

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The role of the MiR-200 family on the tumor suppressor RASSF2 and the effect on MAPK pathway activity in colorectal cancer., Jane V. Carter

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The role of O-GlcNAcase during heart failure., Sujith Dassanayaka

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Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-mediated hypertension., Anastasia Familtseva

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The role and regulation of inhibitor of Kappa B Kinase in the impaired monocyte response., Norman James Galbraith

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Cell-based therapies for ischemic cardiomyopathy : investigations of intramyocardial retention and safety of high dose intracoronary delivery of c-kit positive cardiac progenitor cells, and therapeutic utility of a novel population of cardiac mesenchymal stem cells expressing stage-specific embryonic antigen-3 (SSEA-3)., Matthew C. L. Keith

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The influence of miR-99a on mTOR signaling regulation in colorectal cancer cell lines., Jonathan Rice

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The effects of direct peritoneal resuscitation on leukocyte infiltration after acute brain death., Jessica Lee Weaver

Theses/Dissertations from 2015

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Cardiovascular regulation and effects of respiratory motor training in patients with chronic spinal cord injury., Bonnie Legg Ditterline

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Combination treatment with conjugated linoleic acid and nitrite protects against myocaridal infarction., Natia Qipshidze Kelm

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Development of a vascularized, induced pluripotent stem cell-derived liver-tissue mimic for therapeutic applications., Venkat Madhav Ramakrishnan

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Exercise mitigates the effects of hyperhomocysteinemia on adverse skeletal muscle remodeling., Lee Winchester

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Circulating angiogenic stem cells in diabetes., Nagma Zafar

Theses/Dissertations from 2014

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MiRNA-21 has anti-inflammatory effects in the macrophage response to peritonitis., Rebecca Elise Barnett 1982-

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The role of stem cells in adipose tissue remodeling., Candice ReShay Holden 1988-

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Post-transcriptional regulation of the Type IIA sodium-phosphate cotransporter by parathyroid hormone., Rebecca Dale Murray

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Epigenetic modifications associated with aortic remodeling in hyperhomocysteinemia., Nithya Narayanan

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Myocyte-specific overexpression of stromal cell-derived Factor 1 facilitates cardiac regeneration and improves myocardial function after infarction in mice., Detlef Ernst-Rudolf Obal

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The anti-obesogenic effects of nitric oxide., Brian Edward Sansbury 1985-

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Inflammation-resolving lipid mediators promote revascularization to enhance wound healing., Michael Jingyuan Zhang

Theses/Dissertations from 2012

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Pivotal role of Interleukin-10 on microRNA-155 expression in regulation of the monocyte response in hypothermia., Adrian Theophil Billeter 1984-

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Development of pituitary tumor-transforming gene (PTTG) transgenic mice for the treatment of ovarian cancer., Miranda Y. Fong 1982-

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Hyperhomocysteinemia alters sinoatrial and atrioventricular nodal function : role of the cardiac NMDA receptor., Chirag V. Soni

Theses/Dissertations from 2011

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Partial vs. full support of the heart with a continuous-flow left ventricular assist device : implications for myocardial recovery., Carlo Renato G. Bartoli

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Effects of environmental pollution on endothelial progenitor cells and vascular regeneration., Laura A. Wheat Nissley 1983-

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Pulmonary function and respiratory muscle activation in individuals with chronic spinal cord injury., Daniela Paleville Terson

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Elevation of cardiac glycolysis reduces pyruvate dehydrogenase but increases glucose oxidation., Qianwen Wang

Theses/Dissertations from 2010

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The role of matrix metalloproteinases induced angiogenesis during transition from compensatory cardiac hypertrophy to cardiac failure : therapeutic effects of hydrogen sulfide., Srikanth Givvimani

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Inflammatory cell tumor necrosis factor signaling modulates post-infarction left ventricular remodeling., Robert K. Lewis 1977-

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Cardiac specific transgenic inhibition of nuclear factor-kappaB (NF-kB) mitigates adverse cardiac remodeling and ameliorates cardiac dysfunction in doxorubicin-induced cardiomyopathy., Santosh Kumar Sanganalmath 1977-

Theses/Dissertations from 2009

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The role of O-GlcNAc signaling in acute myocardial ischemia., Gladys Afor Ngoh

Theses/Dissertations from 2008

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The role of protein kinase A in hypoxia-induced PC-12 cell death., Cynthia Jayne Miller

Theses/Dissertations from 2007

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Effects of direct ATP delivery to ischemic skeletal muscle., Federico V. Grossi 1974-

Theses/Dissertations from 2005

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Role of inducible nitric oxide synthase and p-selectin in platelet-arteriolar wall adhesion and associated arteriolar constriction during lung reperfusion., Alexander V. Ovechkin 1957-

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Explore the murine cardiac 20S proteasomes : molecular composition and regulation., Chenggong Zong

Theses/Dissertations from 2004

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The role of the toll-like receptor pathway in susceptibility to inflammatory bowel disease., Nigel Crawford 1974-

Theses/Dissertations from 2003

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Functional proteomic analysis of the myocardial PKCepsilon subproteome PKCepsilon-AKT-eNOS signaling modules and during., Jun Zhang

Theses/Dissertations from 1940

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The effect of distention on blood flow through the intestine., Jack Chumley

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The effect of hypophysectomy on gastric motility in the dog., Edmund A. Smolik

Theses/Dissertations from 1938

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The muscular activity of the small intestine during acute obstruction., Rudolph F. Antoncic

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A study of the relationship between blood flow and limb volume in the hind limb of the dog., J. P. Holt

Theses/Dissertations from 1937

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The effect of drugs on experimental renal hypertension in the dog., J. J. Prusmack

Theses/Dissertations from 1936

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The effect of experimental liver damage on the blood picture of the dog., H. D. Bruner

Theses/Dissertations from 1934

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The role of membranes and phase boundaries in generating electric currents in living tissues., Norman E. Epstein

Theses/Dissertations from 1932

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A study of the movements of the heart and their relationship to the filling of the auricles., John H. Rompf

Theses/Dissertations from 1931

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The influence of the brain upon the liver as a blood concentrating organ in fever., Benjamin F. Aydelotte 1899-1956

Theses/Dissertations from 1930

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Effects of thermal influences upon the pons and medulla and upon the mid brain and diencephalon after ligation of the basilar artery., Franklin Jelsma

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The fate of water lost from the blood in cocaine fever and the relation of this water to the febrile process., Hubert T. Marshall