Date on Master's Thesis/Doctoral Dissertation

5-2006

Document Type

Master's Thesis

Degree Name

M.S.

Department

Health and Sport Sciences

Committee Chair

Olive, Jennifer Lee

Subject

Blood lipids

Abstract

The purpose of this study was to determine if training has a protective effect on endothelial function following the consumption of a high-fat meal. Twenty young males classified as trained or untrained underwent vascular and blood lipid testing pre and post (two- and four-hours) a high-fat meal. Flow mediated dilation was significantly decreased at two- (p < 0.001) and fourhours (p < 0.001) in both groups, with no differences between groups (p = 0.119). Serum TG increased at two- (p < 0.001) and four-hours (p < 0.001) in both groups. LDL-C was reduced at four-hours (p = 0.050) in trained subjects, and two- and four-hours (piÜ 0.01) in untrained subjects. Two-hour HDL-C was reduced compared to baseline (p = 0.024) and four-hours (p = 0.014) in both groups. This study demonstrates that a high-fat meal induces endothelial dysfunction for up to four hours in males, independent of training status.

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