Date on Paper


Document Type

Doctoral Paper

Degree Name




Committee Chair

Dr. Kimberly Meyer

Committee Member

Dr. Elizabeth Burckardt

Author's Keywords

acute kidney injury; contrast medium; cardiac catheterization; serum creatinine; contrast-induced nephropathy


Background: Cardiac catheterizations use intra-arterial contrast media to view the coronary arteries. The use of contrast media can cause contrast-induced nephropathy (CIN). CIN is an abrupt deterioration in renal function that can occur up to 72 hours post-procedure. This diagnosis is associated with increased morbidity and mortality, increased hospital costs, and increased length of stay.

Setting: The project took place in a 432-bed urban facility located in the Midwest region of the United States.

Purpose: The purpose of this QI project was to evaluate if the implementation of an intravenous hydration protocol pre-, intra-, and post-cardiac catheterization decreases the occurrence of CIN.

Procedures: Incidence of CIN at this facility was evaluated via data collection. Rates of CIN were collected 12 months pre-fluid protocol implementation and 11-months post-implementation.

Measures: Serum creatinine levels were measured pre- and post-cardiac catheterization. An elevation in serum creatinine of 25% or more within 48 hours post-procedure constituted a CIN diagnosis.

Results: The rate of CIN for Cohort A was 12.23%. Cohort B was 9.89%. The P value is 0.48. The fluid protocol had no impact on the rates of CIN post-cardiac catheterization.

Schaefer_signed_title_page.pdf (31 kB)
Signed Title Page

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