Effects of sex, cadmium, and high-fat-diet on accumulation of essential metals in mouse kidneys.

Authors

Justin Y. Xu, Department of Medicine, Division Nephrology; Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KYFollow
Adam Gaweda, Department of Medicine, Division NephrologyFollow
Michelle Barati, Department of Medicine, Division NephrologyFollow
Michael Merchant, Department of Medicine, Division NephrologyFollow
Jun Cai, Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KYFollow
Lu Cai, Pediatric Research Institute, Department of Pediatrics, University of Louisville, Louisville, KYFollow
Madhavi Rane, Department of Medicine, Division NephrologyFollow

Document Type

Poster

Publication Date

Spring 2024

Program/Event

Undergraduate Arts and Research Showcase

Abstract

Effects of cadmium and obesity on accumulation of essential metals in mouse kidney were evaluated. Starting in utero and continuing until 24 weeks postweaning, male/female mice were exposed to cadmium (0, 0.5, or 5 ppm) and were fed on Normal Diet (ND)/High-Fat Diet (HFD) post weaning. ICP-MS analysis was performed to evaluate cadmium and essential metals absorbed in the kidneys of aforementioned mice. Metals data obtained was analyzed using MANOVA with multiple comparisons (Bonferroni correction with p

Recommended Citation

Xu, Justin Y.; Gaweda, Adam; Barati, Michelle; Merchant, Michael; Cai, Jun; Cai, Lu; and Rane, Madhavi, "Effects of sex, cadmium, and high-fat-diet on accumulation of essential metals in mouse kidneys." (2024). Undergraduate Research Events. 39.
https://ir.library.louisville.edu/undergradresearch/39