Date on Master's Thesis/Doctoral Dissertation
4-2018
Document Type
Master's Thesis
Degree Name
M. Eng.
Department
Mechanical Engineering
Committee Chair
Kate, Kunal
Committee Co-Chair (if applicable)
Atre, Sundar
Committee Member
Atre, Sundar
Committee Member
Satyavolu, Jagannadh
Author's Keywords
3D Printing; PLA; PEG; Copolymer
Abstract
This thesis is an examination of two material systems derived from polylactic acid (PLA) and polyethylene glycol (PEG). PLA is a polymer commonly sourced from renewable sources such as starches and sugars. It is a relatively strong, biodegradable polymer, making it ideal for use in the body. Even though it has a relative high strength, PLA is also brittle leading to the use of plasticizers to increase flexibility. One such plasticizer is PEG, which is a material that can exist at room temperature as either a thin liquid, or a hard waxy solid depending on the molecular weight. The first chapter of this thesis introduces the goals of the second and third chapters by providing context to the two research projects that were done. The second chapter presents a study on the mechanical properties of 3D printed PLA-PEG blends, using two types of PLA and examining the effects of changing molecular weight of PEG and the concentration of PEG. The third chapter focuses on combining a modified PLA-PEG reaction blend with additional PLA and determining the dissolution profile, as this modified PLA-PEG blend shows some promise as a drug delivery material, due to how quickly it dissolves in water and phosphate buffered saline.
Recommended Citation
Bauer, Jeremiah R., "Materials design with polylactic acid-polyethylene glycol blends using 3D printing and for medical applications." (2018). Electronic Theses and Dissertations. Paper 2886.
https://doi.org/10.18297/etd/2886
Included in
Biology and Biomimetic Materials Commons, Biomaterials Commons, Biomechanical Engineering Commons, Ceramic Materials Commons, Polymer and Organic Materials Commons