Date on Master's Thesis/Doctoral Dissertation

8-2019

Document Type

Master's Thesis

Degree Name

M.S.

Department

Epidemiology and Population Health

Degree Program

Epidemiology, MSE

Committee Chair

Taylor, Kira

Committee Member

Wallis, Anne

Committee Member

Gaskins, Jeremy

Author's Keywords

Female fertility; spontaneous conception; infertility; sexually transmitted infection; probability; reproductive epidemiology

Abstract

This study interrogated predictors of pregnancy and the effect of a history of sexually transmitted infection (STI) on probability of conception among a cohort of women seeking fertility counseling (N=170), using multivariable logistic regression and Cox proportional hazards models. There were 76 (44.7%) total pregnancies. 32 (39.0%) were achieved spontaneously by women who never received ART (N=82). Among women who did receive ART (N=88), 35 (39.7%) were achieved by ART and 9 (10.2%) achieved spontaneously. Among the full cohort (N=170), obesity was a significant negative predictor of pregnancy while history of human papilloma virus was a significant negative predictor of time to pregnancy. Among those who did receive ART (N=88), ovarian infertility diagnosis was a significant positive predictor of pregnancy, relative to other infertility diagnoses. History of STI was nonsignificantly associated with increased probability of pregnancy in all sub-samples, though this result may be confounded by characteristics like coital frequency.

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