Date on Master's Thesis/Doctoral Dissertation
12-2021
Document Type
Master's Thesis
Degree Name
M.S.
Department
Epidemiology and Population Health
Degree Program
Epidemiology, MSE
Committee Chair
Taylor, Kira
Committee Member
Baumgartner, Kathy
Committee Member
DeMarco, Daniel
Author's Keywords
COVID-19; depression; anxiety; Kentucky; mortality
Abstract
Previous studies have shown that mental disorders affect COVID-19 mortality. This study investigated the effect of depression and/or anxiety on COVID-19 outcomes. Depression/anxiety was defined by actively taking medication and/or diagnosis. The outcomes were ICU admission; ventilation; mortality; and time to mortality. Of 698 hospitalized patients, there were 204 (29%) defined to have either depression or anxiety. There were 109 deaths, and of those, 52 (48%) were diagnosed with depression/anxiety. Multivariable logistic regression and Cox proportional hazards models were used to examine associations. ICU admission and ventilation were not significantly associated with depression/anxiety. Depression/anxiety was associated with mortality (OR: 1.84, 95% CI: 1.15-2.93, p: 0.01) and time to mortality (HR: 1.60, 95% CI: 1.07-2.39, p: 0.02), adjusting for age, sex, and history of COPD. The association seemed driven by patients who were never admitted to the ICU. This study showed that depression/anxiety has a significant effect on COVID-19 mortality.
Recommended Citation
Miller, Erica, "The association between depression and anxiety with COVID-19 outcomes." (2021). Electronic Theses and Dissertations. Paper 3790.
https://doi.org/10.18297/etd/3790
