Document Type
Article
Publication Date
6-15-2021
Department
Medicine
Department
Health Management and Systems Sciences
Abstract
Purpose: People living with HIV infection (PLWH) experience increasing risk for non-AIDS diseases including liver dysfunction and injury. Both HIV-infection and heavy alcohol drinking (HAD) are known to cause gut microbial dysbiosis and systemic inflammation that may potentially contribute to altered Gut-Liver axis. However, the specific pathogenic features associated with combinatorial harmful effects of alcohol and HIV infection on gut-liver interactions are not completely understood. This study evaluate the pathogenic changes in the Gut-Liver axis in PLWH with HAD.
Original Publication Information
Volume 45, Issue S1
0145-6008
Alcoholism: Clinical and Experimental Research
(2021), Poster Abstracts. Alcohol Clin Exp Res, 45: 80-262.
Special Issue:44th Annual Speaker & Poster Abstracts of the Research Society on Alcoholism jointly with the International Society for Biomedical Research on Alcoholism, June 2021
June 2021
Pages 80-262
ThinkIR Citation
Ghare, Smita; Bryant, Vaughn; Singhal, Richa; Gautam, Sabina; Tirumala, Chanakya Charan; Reyes-Vega, Andrea; McClain, Craig J.; Cohen, Ronald; Govind, Varand; Cook, Robert L.; and Barve, Shirish, "Assessment of pathogenic changes in the gut-liver axis in plwh with heavy alcohol drinking and gut dysbiosis marked by decreased butyrogenic potential." (2021). Faculty and Staff Scholarship. 961.
https://ir.library.louisville.edu/faculty/961
DOI
doi.org/10.1111/acer.14628
ORCID
0000-0003-1633-6097
Included in
Digestive System Commons, Immune System Diseases Commons, Immunology of Infectious Disease Commons, Internal Medicine Commons, Substance Abuse and Addiction Commons, Virus Diseases Commons
