A 60-year-old male presented to the Emergency Department (ED) with a one-two day history of confusion, headache, and subjective fever. Because he had met with a contact two days prior to admission who had recently traveled from the Bahamas, a COVID-19 nasopharyngeal (NP) and oropharyngeal (OP) polymerase chain reaction (PCR) test was ordered. He was diagnosed with bacterial meningitis based on presenting neurologic symptoms and the identification of Streptococcus pneumoniae from blood cultures. The COVID-19 NP and OP test returned positive, although he never developed shortness of breath, cough, other respiratory symptoms, diarrhea, abdominal pain, nausea, vomiting, or any change in sense of smell or taste. On day three of admission, the patient had improved clinically on intravenous (IV) antibiotics and was discharged home with instructions to self-quarantine. This case demonstrates the possibility of co-infections with COVID-19 and raises the possibility of an association between COVID-19 and patient susceptibility to invasive pneumococcal disease (IPD).
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Patross, Clayton J.; Bohn, Brian C. PharmD; Moore, Sarah E. PharmD; Schulz, Paul; Song, Matthew PharmD, BCIDP; Wilde, Ashley M.; and Ramirez, Julio A.
"Concomitant invasive pneumococcal disease in a patient with COVID-19 – A case report from the Louisville Epidemiology Study,"
The University of Louisville Journal of Respiratory Infections: Vol. 4
, Article 42.
Available at: https://ir.library.louisville.edu/jri/vol4/iss1/42