The Case of a Pregnant Woman with ARDS Due to COVID-19 Treated with Hydroxychloroquine, Azithromycin, and Remdesivir and Delivery of a Healthy Baby During Mechanical Ventilation Through Cesarean Section

Authors

Adria Madera-Acosta, Internal Medicine Residency Goodsamaritan Hospital, Cincinnati, OhioFollow
Martin Gnoni, University of LouisvilleFollow
Bassman Tappuni, Internal Medicine Residency Goodsamaritan Hospital, Cincinnati, OhioFollow
Monika Sadlak, Internal Medicine Residency Goodsamaritan Hospital, Cincinnati, OhioFollow
Ravleen Grewal, Internal Medicine Residency Goodsamaritan Hospital, Cincinnati, OhioFollow
Angel Mena, Internal Medicine Program, Tri-Health Good Samaritan Hospital, Cincinnati, Ohio, USAFollow
Yousef Ali-Ahwel, Critical Care Physician Goodsamaritan Hospital, Cincinnati, OhioFollow

Funder

The author(s) received no specific funding for this work.

Abstract

We are in the midst of a pandemic due to SARS-CoV-2. Pregnancy was identified among the risk factors for worse clinical outcomes in multiple studies. The optimal therapy in this group of patients remains to be defined. Here, we present the case of a 39-year-old Caucasian pregnant female at 31 weeks of gestation, who was treated successfully with hydroxychloroquine, azithromycin, remdesivir, prone therapy, and cesarean delivery of a healthy baby while on mechanical ventilation. She remained SARS-CoV-2-positive until the 39th day of hospitalization. We discuss the pathophysiology of the increased risk of infections during pregnancy and particularly the high risk of microthombosis and coagulopathy due to COVID-19. Ultimately, the contribution of the medications used to the favorable outcomes remains unknown; it is more likely that the delivery helped to resolve the infection.

DOI

10.18297/jri/vol4/iss1/73

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Recommended Citation

Madera-Acosta, Adria; Gnoni, Martin; Tappuni, Bassman; Sadlak, Monika; Grewal, Ravleen; Mena, Angel; and Ali-Ahwel, Yousef (2020) "The Case of a Pregnant Woman with ARDS Due to COVID-19 Treated with Hydroxychloroquine, Azithromycin, and Remdesivir and Delivery of a Healthy Baby During Mechanical Ventilation Through Cesarean Section," The University of Louisville Journal of Respiratory Infections: Vol. 4 : Iss. 1 , Article 73.
DOI: https://doi.org/10.18297/jri/vol4/iss1/73
Available at: https://ir.library.louisville.edu/jri/vol4/iss1/73