The University of Louisville Journal of Respiratory Infections


We are in the midst of a pandemic due to SARS-CoV-2. Pregnancy was identified among the risk factors for worse clinical outcomes in multiple studies. The optimal therapy in this group of patients remains to be defined. Here we present the case of a 39 years old Caucasian pregnant female at 31 weeks of gestation who was treated successfully with hydroxychloroquine, azithromycin, remdesivir, prone therapy, and cesarean delivery of a healthy baby while on mechanical ventilation. The SARS-CoV-2 remained positive until the 39th day of hospitalization. We discussed the pathophysiology of the increase risk of infections during pregnancy and particularly the high risk of microthombosis and coagulopathy due to COVID-19. Ultimately the contribution of the medications used to the favorable outcomes remained unknown being more likely that the delivery helped resolve the infection.


The author(s) received no specific funding for this work.



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Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.



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