This collection includes theses and dissertations from the Department of Bioengineering, in the J.B. Speed School of Engineering. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 (Master of Engineering, prior to 2005) can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please fill out the Electronic Theses & Dissertations form.
Theses/Dissertations from 2024
The examination of intratumoral compression as a mechanobiological driver of glioblastoma progression., Allison McKenzie Johnson
Theses/Dissertations from 2023
Interrogating autism from a multidimensional perspective: an integrative framework., Mohamed T. Ali
Metabolomic differentiation of tumor core and edge in glioma., Mary E. Baxter
Computational fluid dynamics model of hyperthermic intraperitoneal chemotherapy., Olivia Cooney
Development and application of a microfluidic platform for quantifying intra-tumoral compressive stress., Zachary P. Fowler
Quantification of tumor biophysical heterogeneity through mechanical and ultrastructural analysis., Bradley James Mahaffey
Design and evaluation of a multi-functional surgical device for microgravity surgeries., Sienna Shacklette
Investigation of possible inflammatory response after ultrasound and microbubble procedure in the spinal cord., Jenna Wilkerson
Theses/Dissertations from 2022
Establishing the efficacy of non-cellular components of adipose-derived stromal vascular fraction in promoting angiogenesis., Daniel Benson
Release kinetics of metronidazole from 3D printed silicone scaffolds., Sydney E. Herold
Fabrication and characterization of Lactobacillus Crispatus containing bioprints for bacterial vaginosis application., Anthony J. Kyser
Machine learning analysis of acoustic attenuation measurements for cellular characterization., John T. Moore
Acoustofluidic delivery of gene editing compounds for improved immunotherapy processing., Riyakumari K. Patel
Effect of dorsal quadrant or ventral quadrant spinal cord injury on gait features during locomotion., Anya Nicole Trell
Theses/Dissertations from 2021
COVID-19 Serological Diagnostic Development Using A SARS-CoV-2 RBD Foldon Fusion, Joey Emery Breckenridge Jr.
Automated conversion of MultiCellDS Digital Cell Lines and ISA-Tab filesets., Connor Joseph Burns
Conversion of MultiCellDS Digital Snapshots to ISA-Tab format., Corey P. Chitwood
Biomechanical Characterization of Video-Recorded Short-Distance Falls Involving Children Equipped with a Biometric Device in a Childcare Setting: A Pilot Study., Danielle K. Cory
Refinement and automation using algorithmic control of BreathForce, a respiratory training system for patients with spinal cord Injuries., Anna Goestenkors
Update of MultiCellular data standard to match PhysiCell "compact" output., Reid A Honeycutt
CFD analysis of acoustofluidic channels and the effects on biologic delivery., Zachary T. Long
Computational modeling of 3D-printed Lactobacillus-antibiotic scaffolds for bacterial vaginosis., Veeresh P. Rai
Development and evaluation of a body weight support treadmill for use with locomotor training on pediatric spinal cord injury patients., Winston T Rauch
Theses/Dissertations from 2020
An exercise device used to achieve bone formation metrics for the strengthening of the proximal femur., Sean P. Coyle
Mathematical characterization of a microfluidic ultrasound driven transfection device., Chris J. Holton
Evaluation of tracing techniques in the rat spinal cord using a custom MATLAB application., Rachel M. Zalla
Theses/Dissertations from 2019
A deep learning approach to detect diabetic retinopathy in fundus images., Winston R. Furtado
Simulation of a continuum tumor model using distributed computing., Dylan A Goodin
Feasibility study of intelligent LVAD control for optimal heart failure therapy., John A. Karlen III
Non-viral transfection efficiencies for the advancement of CAR-T therapy., Emily M Murphy
Suture-less Trocar Site Closure Clip, Hares A. Patel
Theses/Dissertations from 2018
Optimization of PLGA and PLGA-dasatinib particles through a Taguchi design approach, Rayeanne N Balgemann
Design and development of a multifunctional surgical device for ground and space-based surgical applications., Brooke Elaine Barrow
Tumor-targeted double emulsions for ultrasound-triggered delivery of molecular therapeutics., Connor S Centner
Investigation of cardiovascular tissue following 56Fe-radiation and potential countermeasure effectiveness., Alexandra R DeCarlo
Restoring cholesterol homeostasis in familial hypercholesterolemia cell line model, Lubna Hindi
The effectiveness of localized ultrasound and aptamer surface modification on nanoemulsions for drug delivery to spheroids., Daniel A. Hodge
Investigating the likelihood of pediatric femur fracture due to falls through finite element analysis., Keyonna McKinsey
PLGA-modified nanoparticles for the treatment of hypo-vascularized HPV-related cervical cancers., Lee B. Sims
Rotary pump speed modulation to produce pulsatile flow and ventricular volume unloading., Connor Joseph Smith
Theses/Dissertations from 2017
Development of a directional bone reaming system., Richard J Ackermann
A novel MRA-based framework for the detection of changes in cerebrovascular blood pressure., Yitzhak Atakilt Gebru
Custom software for the 3D printing of patient specific plate bending templates in pelvic fracture repair., Gordon B Lents
Examining the effects of macrophage populations on cancerous tumor growth., Grace E. Mahlbacher
Biomechanical testing of an exercise for strengthening the proximal femur., Alyssa Osbourne
Theses/Dissertations from 2016
Gamma-radiation exposure alters the cardiovascular extracellular matrix., Nicholas Allen
Development and evaluation of custom prosthetic devices for a companion animal utilizing additive manufacturing., Benjamin Joseph Cahill
Efficacy of subcutaneous electrocardiogram leads for synchronous timing and aortic root cannulation for chronic counterpulsation therapy., Stephen R. Carnahan
Development of a novel device for ventricular assist device outflow graft anastomosis., Young Choi
Foot strike patterns and body alignment effects on muscle activity during running., Nicole Knapp
Fabrication, characterization and skin permeation of antoxidant-loaded lipid vesicles for transdermal drug delivery., Emily Martin
Automated analysis of cancerous histological samples., Thomas Allen Tennill
Theses/Dissertations from 2015
Novel biomechanical test method for cancellous bone screws and screw augmentation with cement., Kevin Lancaster
Fibroblast-derived extracellular matrix: an alternative cell culture substrate that alters lung cancer cell line phenotype., Michael Thomas Scherzer
Synthesis, optimization, and degradation of a fish glue/PLGA polymer., Adam T. Schworer 1989-
Development of a neuromusculoskeletal computer model in a chondrodystrophic dog., Gregory Russo States
Theses/Dissertations from 2014
Development of an application for patient-centered dementia care., David Collar Alston
Synthesis of a drug delivery vehicle for cancer treatment utilizing DNA-functionalized gold nanoparticles., Tyler Brann
Fabrication and characterization of antioxidant loaded liposomes., Brian Gettler
Development of novel methods for analysis of autonomic balance and gamma coherence in autism., Marie Katherine Hensley
Personalized anticoagulant management using reinforcement learning., Michael Jacobs
Crosslinking albumin for drug release from spray dried particles., Ishita Jain
Theses/Dissertations from 2013
Human powered Knudsen pump for pneumatic pharmaceutical delivery., Alexander Donovan Bell
Development of a physiologic ex vivo vessel perfusion system., Mitchell J. Buller
Evaluation of drug release from Abraxane and Doxil in tumor tissue., Michael Christopher Clark
Biomodeling of pancreatic tumor mass., Justin Lee Howell
Production of high yield gold/gold-sulfide nanoparticles via cellulose membrane., Kurtis T. James
An improved thin-film microelectrode array and signal conditioning board for measuring cardiac surface potentials., Christopher Hayward Osborne
Surface bound PEG-RGDS on PEG-DA hydrogels and its effects on RPE cell morphology and differentiation., Jeremy E. Phillips
Development of novel layered nanoparticles for more efficient cancer treatment., Thomas A. Priest
Apical left ventricular cannula sutureless implantation development., Adam D. Scarsella
Ventricular assist device and extracellular matrix combination therapy in a chronic ischemic heart failure bovine model., Erin F. Smith
Automated testsystem of COGNISION headset for cognitive diagnosis., Joshua I. White
Pulsatile flow does not improve efficacy in ex vivo lung perfusion., Keith A. Zoeller
Theses/Dissertations from 2012
Removal of electrocardiographic corruption from electromyographic signals using a localized wavelet based approach., Nihit Bajaj
Effect of flow on human endothelial cell and dermal cell growth rates supplemented with drug infused media., Daniel Baumann
Carbon nanotube biosensors for detection of biomarkers in breast cancer cells., Benjamin C. King
The VEGF quadruplex-forming sequence inhibits lung cancer cell growth., Edward David Muench 1987-
A novel high yield process for gold sulfide nanoparticle synthesis via shifting equilibrium of self-assembly reaction., Dhruvinkumar Patel
Theses/Dissertations from 2011
Quantification of vascular perfusion in the spinal cord after injury., Ruthie S. Fligor
Feasibility of subcutaneous ECG leads for synchronized timing of a counterpulsation device., Sean P. Warren
Theses/Dissertations from 2010
Investigation of high-frequency ultrasound biomicroscopy for examining arteriopathy in hand transplant patients., Emily Renee Cox 1987-
Treatment of severe aortic stenosis : experimental design, testing, and analysis of an aortic valve bypass apical cannula., Joel Douglas Graham
Development of EEG gama indicies of cue reactivity to assess functional outcomes of neurofeedback training in substance use disorder., Timothy Joseph Horrell
Shape-based detection of cortex variability for more accurate discrimination between autistic and normal brains., Matthew Joseph Nitzken 1987-
Chitosan nanoparticles to encapsulate a biofilm degrading enzyme for treatment of CRBSI., Lindsay Nicole Strotman
