This collection includes theses and dissertations from the Department of Bioinformatics and Biostatistics, in the School of Public Health & Information Sciences. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please fill out the Electronic Theses & Dissertations form.

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Theses/Dissertations from 2023

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Statistical methods for assessing treatment effects on ordinal outcomes and selecting optimal treatment on survival outcomes using observational data., Huirong Hu

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Causal inference for the effect of continuous treatment on time-to-event outcomes and mediation analysis on health disparities in observational studies., Triparna Poddar

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Statistical inference on lung cancer screening using the national lung screening trial data., Farhin Rahman

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Bayesian strategies for propensity score estimation in causal inference., Uthpala I. Wanigasekara

Theses/Dissertations from 2022

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Bayesian methods for graphical models with neighborhood selection., Sagnik Bhadury

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Bayesian methodologies for constrained spaces., Siddhesh Kulkarni

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Statistical methods for personalized treatment selection and survival data analysis based on observational data with high-dimensional covariates., Don Ramesh Dinendra Sudaraka Tholkage

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Statistical methods for assessing drug interactions and identifying effect modifiers using observational data., Qian Xu

Theses/Dissertations from 2021

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Estimating treatment effect on medical cost and examining medical cost trajectory using splines and change point techniques., Indranil Ghosh

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Observational studies in group testing and potential applications., Alexander Christopher Noll

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Estimating cumulative incidence rate on interval censored data in an illness-death model., Chen Qian

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Predictive modeling of clinical outcomes for hospitalized COVID-19 patients utilizing CyTOF and clinical data., Onajia Stubblefield

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Bayesian variable selection strategies in longitudinal mixture models and categorical regression problems., Md Nazir Uddin

Theses/Dissertations from 2020

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Aspects of causal inference., John A. Craycroft

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Marginal methods and software for clustered data with cluster- and group-size informativeness., Mary Elizabeth Gregg

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Novel Bayesian methodology for the analysis of single-cell RNA sequencing data., Michael Sekula

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Modified-half-normal distribution and different methods to estimate average treatment effect., Jingchao Sun

Theses/Dissertations from 2019

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Novel Bayesian methodology in multivariate problems., Debamita Kundu

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Statistical methods for estimating and testing treatment effect for multiple treatment groups in observational studies., Xiaofang Yan

Theses/Dissertations from 2018

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Generalized spatiotemporal modeling and causal inference for assessing treatment effects for multiple groups for ordinal outcome., Soutik Ghosal

Theses/Dissertations from 2017

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Functional data analysis methods for predicting disease status., Sarah Kendrick

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Estimation of the three key parameters and the lead time distribution in lung cancer screening., Ruiqi Liu

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Sample size calculations and normalization methods for RNA-seq data., Xiaohong Li

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Novel statistical approaches for missing values in truncated high-dimensional metabolomics data with a detection threshold., Jasmit SureshKumar Shah

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Bayesian approach on short time-course data of protein phosphorylation, casual inference for ordinal outcome and causal analysis of dietary and physical activity in T2DM using NHANES data., You Wu

Theses/Dissertations from 2016

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Propensity score based methods for estimating the treatment effects based on observational studies., Younathan Abdia

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Inference for a zero-inflated Conway-Maxwell-Poisson regression for clustered count data., Hyoyoung Choo-Wosoba

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Propensity score methods : a simulation and case study involving breast cancer patients., John Craycroft

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Expression of genes for peptide/protein hormones and their cognate receptors in breast carcinomas as biomarkers predicting risk of recurrence., Michael Wesley Daniels

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Some contributions to nonparametric and semiparametric inference for clustered and multistate data., Sandipan Dutta

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A log rank test for clustered data under informative within-cluster group size., Mary Elizabeth Gregg

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Semi-parametric methods for personalized treatment selection and multi-state models., Chathura K. Siriwardhana

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Integrated analysis of miRNA/mRNA expression and gene methylation using sparse canonical correlation analysis., Dake Yang

Theses/Dissertations from 2015

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Evaluation of liver transplant prioritization methods for hepatocellular carcinoma patients using multistate models., Sarah Katharine Alver

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Novel applications of and extensions to linear regression methods for the biomedical and materials sciences., Joe Bible

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Summary of survival analysis with SAS procedures., Derek Duane Childers 1990-

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OptCluster : an R package for determining the optimal clustering algorithm and optimal number of clusters., Michael N. Sekula

Theses/Dissertations from 2014

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Classification of clinical outcomes using high-throughput and clinical informatics., Alexander Carswell Cambon

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Statistical methods for assessing treatment effects for observational studies., Kristopher C. Gardner 1984-

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Patient rule induction method for subgroup identification given censored data., Patrick James Trainor

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Penalized regressions for variable selection model, single index model and an analysis of mass spectrometry data., Yubing Wan

Theses/Dissertations from 2013

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Novel methods based on regression techniques to analyze multistate models and high-dimensional omics data., Sutirtha Chakraborty

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Simulation study for the lead time in cancer screening when human lifetime is a competing risk., Sarah K. Kendrick

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Preliminary assessment of a school-based healthy lifestyle program among rural children., Jiying Ling

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Compound identification using penalized linear regression., Ruiqi Liu

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Generalized estimating equation based zero-inflated models with application to examining the relationship between dental caries and fluoride exposures., Sheng Xu

Theses/Dissertations from 2012

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Propensity score matching for surgical outcomes with observational data., Robert M. Cannon 1983-

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The trends and disparities in the diagnosis of breast cancer by mobile mammography at a comprehensive cancer center., Dianhong Luo

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Analysis of microRNA microarray (MM chip) data for aging mice models., Vikranth Shetty

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Utility of a goodness-of-fit index for the graded response model with small sample sizes : a Monte Carlo investigation., Christina Ruth Studts 1971-

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Application of linear mixed-effects models to crossover designs., Lei Zhou

Theses/Dissertations from 2011

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Mixed-effects models for modeling cardiac functions and treatment effects., Hyejeong Jang

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Regression methods for survival and multistate models., Farida Mostajabi

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The cost-effectiveness of the Kentucky pilot project of allowing primary PCI at hospitals without onsite CABG capabilities., Pedro Ramos

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Design and inference in phase II/III clinical trials incorporating monitoring of multiple endpoints., Herman E. Ray

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An adaptive ensemble learner function via bagging and rank aggregation with applications to high dimensional data., Jasmit SureshKumar Shah

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Determining the most effective way in which to manage congestive heart failure patients., Beatrice Ugiliweneza

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Consistency of differentially expressed gene rankings based on subsets of microarray data., Dake Yang

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Evaluation of methods for analyzing gene-gene interaction data for survival outcomes., Jie Zhang

Theses/Dissertations from 2010

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A phase II two stage clinical trial design to handle latent heterogeneity for a binary response., Christopher Noel Barnes

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Does Health Hoops Kentucky improve the health of children with asthma?, Yu-Ting Chen 1982-

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Evaluate experiences necessary to achieve proficiency in advanced fiberoptic intubation skills : can we accelerate the learning curve with simulator training?, Xinyuan Duan

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Inference for time to event and sojourn time data under right censoring using reweighting approaches., Jie Fan

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Placebo effect for low back pain : a meta-analysis., Matthew Aaron Lanham 1982-

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An investigation of sliced inverse regression with censored data., Daniel W. Riggs

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Comparison of different methods for longitudinal data with missing observations., Lin Sun

Theses/Dissertations from 2008

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Clustered longitudinal data analysis., Ming Wang

Theses/Dissertations from 2007

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Polycyclic aromatic hydrocarbons in maternal and cord blood plasma., Paula G. Radmacher 1951-

Theses/Dissertations from 2006

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Cost-comparison of prostate cancer screening versus not screening., Bill Fell 1951-

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Text mining comorbidity codes in the analysis of cardiopulmonary rehabilitation data., Jennifer Ferrell 1982-

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Multiobjective simulation-based methodologies for medical decision making., Ahmed Hassan YoussefAgha

Theses/Dissertations from 2004

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The analysis of missing data in public use survey databases : a survey of statistical methods., Ping Xu 1975-

Theses/Dissertations from 2003

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A Markov model of secondary prevention of osteoportic hip fractures., Stephanie Tapp