Abstract
Chronic stress can be characterized as a prolonged stressor that negatively impacts one’s life and has been associated with a variety of adverse health outcomes, including cardiovascular disease and immune system suppression. Given that chronic stress undeniably impacts health as a whole, it is reasonable to assume that it may also affect the aging process. The purpose of this literature review is to investigate the impact of chronic stress on the aging process with a specific focus on the 12 hallmarks of aging: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis. Chronic stress was found to affect all of the hallmarks of aging, and interventions for stress-induced advanced aging include physical activity, caloric restriction, mindfulness, and meditation.
Recommended Citation
Alfieri, Toriana
(2024)
"The Impact of Chronic Stress on the Aging Process,"
The Cardinal Edge: Vol. 2:
Iss.
1, Article 14.
Available at:
https://ir.library.louisville.edu/tce/vol2/iss1/14
