Volume 3, Issue 1 (2025) Issue 1
Dear Reader,
It brings me great joy to present the first issue of Volume 3 of The Cardinal Edge (TCE), the University of Louisville’s pioneering undergraduate research journal. TCE provides a platform for students to showcase their invaluable contributions as the next generation of thinkers, creators, and leaders to the ever-growing research community at UofL. The work of UofL students showcases their ability to engage in meaningful academic discussions with peers, faculty, and community discourse around the globe.
This year’s issue covers a wide range of topics, traveling back in time to consider the work of Aristotle to the present understanding of the nuclear function in Parkinson’s disease. This issue also includes three spotlight interviews highlighting faculty research addressing topics of neuroplasticity of the brain, glioblastoma, and the role of AI in modern engineering research. We proudly announce TCE’s Best Paper of 2024-25, Asimina triloba (L.) Dunal: The Complete Story of America’s Forgotten Fruit, a study of the fruit commonly known as pawpaw to understand its agricultural and ecological benefits.
During this publication cycle, TCE increased our staff by fifteen first-year members and worked with countless graduate students and faculty reviewers, whose insight and expertise continue to serve as the foundation of our journal. Partnering with the Center for Engaged Learning, we have continued with the publication of the third supplemental issue to the journal, which will feature 30 abstracts from UofL’s undergraduate research symposiums.
We would like to express our gratitude to our faculty advisor, Dr. Mark Running whose continuing guidance and advice has been pivotal to TCE’s success. We are also grateful to Dr. Paul DeMarco, Director of the Center for Engaged Learning, for his sponsorship and support. Alongside the staff of the CEL and the ThinkIR team who have been a tremendous anchor in making this journal possible. Thank you to our researchers, reviewers, and most importantly, you—the reader—for supporting undergraduate research and innovation at UofL.
In my time as the Executive Editor-in-Chief of TCE, I have been in awe of the commitment and hard work of our journal staff. I am immensely grateful to my fellow editor-in-chief, editorial advisor, managing editors, and cohort team members for their diligence and passion in pushing us through this cycle as we continue to uphold the legacy left by our founding members. I am beyond excited to have served as an editor of TCE and look forward to witnessing its role in fostering a thriving undergraduate research community at UofL.
Happy Reading,Happy reading,
Yaara Aleissa
Executive Editor-in-Chief
Gita Jaikumar
Associate Editor-in-Chief
Kamal Amirneni
Senior Editorial Advisor
Lindsey Lankford
Design Managing Editor
Preeti Tanwani
Review Managing Editor
Sireen Khader
Spotlight Managing Editor
Hailey Turiczek
Outreach Managing Editor
Brief Research Reports
The Silent Epidemic: How E-Cigarettes and Policy Gaps Endanger Public Health
Fizzah Syed, Saumya Sikhwal, and Priya Viswakumar
Leaf Droppage Delayed in Sugar Maple Trees on an Urban to Rural Gradient
Isabella S. Bastien and Isabella Bastien
Faculty Spotlights
Targeting Glioblastoma: Mechanistic and Clinical Perspectives from UofL Research
Swetha Senthil Nathan
Full-length Research Reports
Development and Preliminary Pressure Control Validation of WoundWatch: NPWT System with Remote Monitoring Capabilities
Swetha Senthil Nathan
The Kennedy Familys' Influence on the Passage of the Immigration and Nationality Act of 1965
Jillian Wallshield
Making a Victim: The Quest to Define Austria in a Cold War Context
Katherine E. White
Fear and Freedom: California Gay Bars in the 1960s
Bridget L. Kelley
Literature Reviews
Lamin A/C and LINC Complex expression affects nuclei's mechanical properties and functions in Osteosarcoma
Shridha Rajeswar
Chief Editorial Board
Sai Jeyaprakash, Executive Editor-in-Chief
Harshith Jella, Associate Editor-in-Chief
Yaara Aleissa, Senior Editorial Advisor
Emma Fellows, Design Managing Editor
Sireen Khader, Spotlight Managing Editor
Kusum Kumar, Review Managing Editor
Hailey Turiczek, Outreach Managing Editor
Design Cohort
Alexis Abboud, Team Member
Kendall Neundorfer, Team Member
Spotlight Cohort
Rianna Pais, Team Member
Fizzah Syed, Team Member
Saumya Sikhwal, Team Member
Swetha Senthil Nathan, Team Member
Priya Viswakumar, Team Member
Review Cohort
Brody Johnson, Team Member
Rayan Haq, Team Member
Sol Jetter, Team Member
Adnan Shaik, Team Member
Nathan Woolery, Team Member
Outreach Cohort
Benjamin Mackay, Treasurer, Team Member
Sabeen Nadeem, Team Member
Veena Pendyala, Team Member, Treasurer
Savannah Thompson, Team Member
Faculty Advisors
Dr. Mark Running, Department of Biology
Journal Sponsor
Dr. Paul DeMarco, Center of Engaged Learning
Special thanks to Mahathi Gavuji for designing TCE's logo!
For questions or comments please contact cardedge@louisville.edu