Welcome to The Cardinal Edge!
The Cardinal Edge is UofL's only faculty-reviewed and peer-reviewed multidisciplinary undergraduate research journal aimed to showcase and celebrate the novel student research conducted at UofL. TCE aims to prepare undergraduate students for future publishing endeavors by allowing students to participate as both authors and editors.
We are committed to publishing faculty or peer-reviewed original research articles, reviews, and commentaries. More detailed descriptions of the journal content can be found on the Aims and Scope page.
Current Issue: Volume 3, Issue 2 (2025) Issue 2 Supplemental
Letter From the Editors
Dear Reader,
It brings me great joy to present the first issue of Volume 3 of The Cardinal Edge (TCE), the University of Louisville’s pioneering undergraduate research journal. TCE provides a platform for students to showcase their invaluable contributions as the next generation of thinkers, creators, and leaders to the ever-growing research community at UofL. The work of UofL students showcases their ability to engage in meaningful academic discussions with peers, faculty, and community discourse around the globe.
This year’s issue covers a wide range of topics, traveling back in time to consider the work of Aristotle to the present understanding of the nuclear function in Parkinson’s disease. This issue also includes three spotlight interviews highlighting faculty research addressing topics of neuroplasticity of the brain, glioblastoma, and the role of AI in modern engineering research. We proudly announce TCE’s Best Paper of 2024-25, Asimina triloba (L.) Dunal: The Complete Story of America’s Forgotten Fruit, a study of the fruit commonly known as pawpaw to understand its agricultural and ecological benefits.
During this publication cycle, TCE increased our staff by fifteen first-year members and worked with countless graduate students and faculty reviewers, whose insight and expertise continue to serve as the foundation of our journal. Partnering with the Center for Engaged Learning, we have continued with the publication of the third supplemental issue to the journal, which will feature 30 abstracts from UofL’s undergraduate research symposiums.
We would like to express our gratitude to our faculty advisor, Dr. Mark Running whose continuing guidance and advice has been pivotal to TCE’s success. We are also grateful to Dr. Paul DeMarco, Director of the Center for Engaged Learning, for his sponsorship and support. Alongside the staff of the CEL and the ThinkIR team who have been a tremendous anchor in making this journal possible. Thank you to our researchers, reviewers, and most importantly, you—the reader—for supporting undergraduate research and innovation at UofL.
In my time as the Executive Editor-in-Chief of TCE, I have been in awe of the commitment and hard work of our journal staff. I am immensely grateful to my fellow editor-in-chief, editorial advisor, managing editors, and cohort team members for their diligence and passion in pushing us through this cycle as we continue to uphold the legacy left by our founding members. I am beyond excited to have served as an editor of TCE and look forward to witnessing its role in fostering a thriving undergraduate research community at UofL.
Happy reading,
Yaara Aleissa
Executive Editor-in-Chief
Gita Jaikumar
Associate Editor-in-Chief
Kamal Amirneni
Senior Editorial Advisor
Lindsey Lankford
Design Managing Editor
Preeti Tanwani
Review Managing Editor
Sireen Khader
Spotlight Managing Editor
Hailey Turiczek
Outreach Managing Editor
Research Abstracts
A Novel Arsenic Methyltransferase Splice Variant Expressed in Human Keratinocytes
Caitlin H. Reynolds, Alexandra N. Nail, Miroslav Styblo, Peter Cable, and J. Christopher States
An Examination of the Relationships Between Types of Strain and Substance Misuse Among Queer Adults
Mckenzie T. Nguyen and Katelyn Mcmahon
Depression, Belonging, and Self-Censorship about Palestine Among Arab Americans
Ghadir Habeeb, Amanda Jiang, Batool Alderawi, Yara Mekawi, and Nadia Al-Dajani
The Effect of Prenatal Cigarette Smoke Exposure and Adult High-Fat/High-Fructose Diet on Liver Triglyceride Levels
Toni A. Adedokun, Isaiah Burciaga, Megan Jacobs, Katelyn Chism, Anna-Lee Harris, Kristen Overton, Selma Podbicanin, Andrew Potts, Rachel Neal, and Cynthia Corbitt
The Resilient Families Project: Promoting Resilience, Mindfulness and Belonging through Community Engagement and Interactive Reading in At-Risk Adults
Sydney Higdon; Dillon Hepler; Lora D. Haynes, Ph.D.; and Angela Ely, B.A.
Urban Areas are Associated with Earlier Breeding Timing in American Robins
Lola Hackle, Jennifer Wickes, Elise Mittlestat, Ashley Stine, Keegan Abeson, Carolina Villalona, and Mikus Abolins-Abols
Stress and Sleep in a Community Sample of Preschool-Aged Children
Khadija Awale, Akira Isaac M.S., Alyssa Rodriguez M.S., and Sara Bufferd Ph.D.
Experience with a Systematic Review Project from an Undergraduate Student Perspective
Maggie Schade, Bianca Welikson, and Maria Kondaurova
Effects of Salinity on interactions between Epichloë amarillans and Fusarium spp. In American Beachgrass
Emma G. Mills, Dylan Habeeb, Natalie Christian, and Connor Morozumi
Impact of Legacy AMF Communities On Vegetative Growth & Yield Of Soybean
Dylan Habeeb, Connor Morozumi, and Natalie Christian
Light as an Environmental Toxin: Impacts of Temporal Circadian Misalignment on Physiology, Behavior, and Lifespan in Drosophila
Aubrey Reitzel, Krish Patel, Breanna Beard, and Dae-Sung Hwangbo
Effects of Phosphorus Addition on Fungal Colonization in Little Bluestem
Isabel M. Zanartu, Alexx Nicholas, McKenzie Goodwyn, and Connor Morozumi
HSP90 Inhibitor in Reducing Integrated Stress Response in an Experimental Mouse Model of Spinal Cord Injury
Yousef Abozaid, Aditya Sarkar, Lukasz P. Slomnicki, and Michal Hetman
The Impact of Linguistic Discrimination on the Mental Health of International College Students: A Systematic Review Protocol Design
Isabella G. Hausladen, Chinarah D. Winston, Maria Kondaurova, and Lidiya Grote
High Polarization in Narrow Line Seyfert 1 Galaxy IRAS 1239.7+3333
Bryn Connelly and Dirk Grupe PhD
Analyzing the Climate-Growth response of Hemlock Species in Tight Hollow, Daniel Boone National Forest, Kentucky, USA
Jacob G. Brown
Exploring the Impact of Perceived Patient Age and Gender on Medical Students' Comfort and Confidence with Sexual History-Taking
Haven Gabrielle V. Romero and Laura Weingartner
EGF Enhances Re-Epithelization in our Ex-Vivo Pig Eye Model
Andrew D. Le, Lisandra Plana-Ramos, Kate Tarvestad, and Brian Ceresa
Activation of Autophagy in Human Neutrophils in Response to Emerging Oral Pathogen Peptoanaerobacter stomatis
Mya Philipose, Shikha Srivastava, and Silvia Uriarte
Patient presentation affects medical student comfort during sexual health encounters
Harshith Jella, Emily J. Noonan, and Laura Weingartner
How Medical Students Use Comforting Language when Taking a Sexual History for Different Presenting Complaints
Abigail Breeze, Emily J. Noonan, and Laura Weingartner
Galaxy Zoo: A Catalog of ~1000 Occulting Pairs in the DESI Legacy Survey for Dust Studies
Trevor A. Butrum and Benne Holwerda
Filifactor alocis Disrupts Efferocytosis to Sustain Inflammation in Periodontitis
Ella Dye, Silvia Uriarte, and Ruth Idowu
Evolving Solutions for Red Blood Cell Preservation
Ali Alkafaji, Charles A. Elder, Mohammad Zaidi, Kavin Parthiv, and Michael A. Menze
Settler Colonialism: A Case-Study Analysis of Dam Infrastructure in the American West
Kassidy Haynes and Carrie Mott
Nursing Interventions to Reduce Anxiety and Psychological Distress in Breast Cancer Patients in the US
Alexis Abboud and Al Araydeh Mifleh
Chief Editorial Board
Sai Jeyaprakash, Executive Editor-in-Chief
Harshith Jella, Associate Editor-in-Chief
Yaara Aleissa, Senior Editorial Advisor
Emma Fellows, Design Managing Editor
Sireen Khader, Spotlight Managing Editor
Kusum Kumar, Review Managing Editor
Hailey Turiczek, Outreach Managing Editor
Design Cohort
Alexis Abboud, Team Member
Kendall Neundorfer, Team Member
Spotlight Cohort
Rianna Pais, Team Member
Fizzah Syed, Team Member
Saumya Sikhwal, Team Member
Swetha Senthil Nathan, Team Member
Priya Viswakumar, Team Member
Review Cohort
Brody Johnson, Team Member
Rayan Haq, Team Member
Sol Jetter, Team Member
Adnan Shaik, Team Member
Nathan Woolery, Team Member
Outreach Cohort
Benjamin Mackay, Treasurer, Team Member
Sabeen Nadeem, Team Member
Veena Pendyala, Team Member, Treasurer
Savannah Thompson, Team Member
Faculty Advisors
Dr. Mark Running, Department of Biology
Journal Sponsor
Dr. Paul DeMarco, Center of Engaged Learning
Special thanks to Mahathi Gavuji for designing TCE's logo!
For questions or comments please contact cardedge@louisville.edu