This collection includes theses and dissertations from the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please fill out the Electronic Theses & Dissertations form.
Theses/Dissertations from 2019
Development of BAR-peptide nanoparticles and electrospun fibers for the prevention and treatment of oral biofilms., Mohamed Yehia Mahmoud
Preference for odor-taste mixtures is dependent on previous experience., Kelsey Allison McQueen
Investigation of phosphoserine aminotransferase 1(PSAT1) in breast cancer progression., Stephanie Metcalf
Glycine receptor expression across identified retinal ganglion cell types., Ian Scot Pyle
A recombinant cholera toxin b subunit variant (CTB-KDEL) exhibits unique colon mucosal healing effects that have therapeutic implications for inflammatory bowel disease., Joshua Mark Royal
Characterizing the role of extracellular matrix in non-small cell lung carcinoma metastasis using a 3D microenvironment mimetic in-vitro culture system., Douglas John Owulaku Saforo
Characterizing the roles of neutral ceramidase in cisplatin-induced kidney injury., Sophia M. Sears
The self-efficacy of biological mothers and foster mothers caring for infants prenatally exposed to drugs or treated for NAS : examination of potentially influencing factors., Megan Kathleen Sherehiy
The effect of spinal cord injury on sexual function., Casey J. Steadman
Electrospun fibers and nanoparticles for the prevention of sexually transmitted infections., Kevin Michael Tyo
The manipulation of host transcription by the ANKH effector of legionella., Juanita E. Von Dwingelo
Paraoxonase 2 is critical for non-small cell lung carcinoma proliferation., Aaron Whitt
Theses/Dissertations from 2018
Nutritional virulence of Legionella pneumophila., Ashley M. Best
Unfolded protein response pathways in skeletal muscle homeostasis., Kyle R. Bohnert
Deciphering the role of human arylamine N-acetyltransferase 1 (NAT1) in breast cancer cell metabolism using a systems biology approach., Samantha Marie Carlisle
The migration and developmental remodeling of intrinsic interneurons in visual thalamus and the role of retinal signaling., Naomi E. Charalambakis
The role of aldehyde dehygrogenase 2 in liver injury caused by vinyl chloride and high-fat diet., Liya Chen
Functional and structural impact of the loss of the leucine-rich repeat protein LRIT1 in the mouse retina., Catherine Ann Cobb
CD11b regulation of B cell receptor signaling in health and systemic lupus erythematosus., Paul Lorenzo Dascani
Characterizing the gut microbiota during plasmodium infection and antimalarial treatment., Joshua E. Denny
Maturation of human induced pluripotent stem cell derived engineered cardiac tissues using chief transfection and chronic optical pacing., Marc M. Dwenger
A cancer-targeted gold nanoparticle-based MRI contrast agent., Nagwa El-Baz
The N-terminal methyltransferase homologs NRMT1 and NRMT2 exhibit novel regulation of activity through heterotrimer formation., Jon David Faughn
Traumatic brain injury : investigating misconceptions among graduate students in physical therapy, occupational therapy, and speech-language pathology., Michael Frazure
EGFR signaling from the early endosome., Julie A. Gosney
Epidermal growth factor receptor (EGFR) inhibition by polychlorinated biphenyls contributes to non-alcoholic fatty liver disease (NAFLD)., Josiah Hardesty
Inflammasome independent leukotriene-b4 production drives crystalline silica induced sterile inflammation., Bindu Hegde
Autism spectrum disorder : investigating predictive diagnostic relationships in children three years-of-age and younger., Kaitlin Juergensen
Swallow and breathing coordination following suprahyoid muscle injury., Bradley Kimbel
Assessing the role of arsenite in disrupting the EGFR signaling axis., Christine Kim
Vinyl chloride enhances diet-induced liver injury via metabolic dyshomeostasis : critical role of mitochondria., Anna L. Lang
A study of GPR3, GPR6, of GPR12 as novel molecular targets for cannabidiol., Alyssa S. Laun
Effects of hydrogen sulfide in hyperhomocysteinemia-mediated skeletal muscle myopathy., Avisek Majumder
Perinatal nicotine with or without early life influenza infection leads to lung dysfunction with age., Ryan Carroll McAllister
A new surgical approach for O-C2 fusion, solving the problem of dysphagia., M. Kathryn McClure
Evaluation of drug-loaded gold nanoparticle cytotoxicity as a function of tumor tissue heterogeneity., Hunter Allan Miller
Influence of bilberry-derived anthocyanidins on key regulators of colorectal cancer development., Ashley M. Mudd
Alpha-amino methylation and acetylation are novel regulators of MYL9 function., Christopher David Nevitt
Cholesterol metabolism and statin effects on an FH class II LDL-receptor mutation., Linda Omer
Wnt/β-Catenin mediated cancer stem cell activation in hepatocellular carcinoma., Harshulkumar M. Pandit
Divergent evolution of di-lysine ER retention vs. farnesylation motif-mediated anchoring of the ankb virulence effector., John David Perpich
Role of TrkB-signaling in taste development and function., Jennifer Rios-Pilier
Therapeutic potential of a plant-made cholera toxin b subunit variant for the treatment of ulcerative colitis., Joshua Mark Royal
Epidermal growth factor-like ligands regulate dimer selection., Jamie S. Rush
Characterization of type II toxin anti-toxin systems in Aggregatibacter actinomycetemcomitans., Blair W. Schneider
Feeding behaviors and the child with posterior tongue-tie : comparison to norms., McKenzie Sexton
A clinically relevant mouse model of cisplatin-induced kidney injury., Cierra Nichole Sharp
Investigating the impact of NRMT1 cancer mutants on catalytic specificity and the DNA damage response., Kaitlyn Marie Shields
Organization and development of cholinergic input to the mouse visual thalamus., Guela Sokhadze
Canonical nuclear factor-κB signaling in satellite stem cell homeostasis and function., Alex R. Straughn
Exercise preconditioning and TFAM overexpression diminish skeletal muscle atrophy., Nicholas Todd Theilen
Particulate hexavalent chromium does not induce centrosome amplification in sperm whale and bowhead whale cells., Jennifer Haruka Toyoda
Characterizing the virulence factor YapE in Yersinia pestis., Tiva Templeton VanCleave
Functional consequence of PSAT1 association on PKM2's inherent enzymatic activity., Alexis Avidan Vega
The involvement of epithelial cells in arenavirus-induced pathogenesis., Nikole Leslie Margaret Warner
Tissue engineered micro and macrovasculature utilizing stromal vascular fraction., Joseph Samir Zakhari
Theses/Dissertations from 2017
MiRNA expression changes in arsenic-induced skin cancer in vitro and in vivo., Laila Al-Eryani
Characterization of Filifactor alocis and its immune evasion strategies employed against human neutrophils., Cortney Linn Armstrong
Enhancing cell therapy for ischemic cardiomyopathy., Michael J. Book
Neural coding of natural and synthetic speech., Allison Brown
PCB-associated steatohepatitis and the role of nuclear receptors., Heather Brooke Clair
Spinal cord injury induced cardiac decline and the limitations of exercise., Kathryn Michele DeVeau
Spontaneous vocal matching in mothers and their hearing impaired infants with cochlear implants : a quantitative analysis., Lydia Doggett
The effects of moderate alcohol consumption and inflammation on the hepatic matrisome and the renal cortex proteome., Christine E. Dolin
Metabolic regulation of myocardial adaptation to exercise., Andrew Alan Gibb
Age-related host factors regulate lung cancer progression., John Caleb Greenwell
Targeting the glucose metabolism of myeloid-derived suppressor cells (MDSCs) to stimulate cancer immunity., Jaspreet Grewal
Targeting the major regulator of mitosis., J. Mason Hoffman
Diffusion-weighted magnetic resonance imaging in diagnosing graft dysfunction : a non-invasive alternative to renal biopsy., Elizabeth Marie Hollis
Identifying the signaling mechanisms of EGFR-mediated apoptosis., Nicole Marion Jackson
Advances in tumor-targeted therapy using nanomedicine., Divya Karukonda
Stretching adversely modulates locomotor capacity following spinal cord injury via activation of nociceptive afferents., Anastasia V. Keller
Mitochondrial Transcription Factor A's role in heart failure., George H. Kunkel
UBQLN1 : a multi-domain protein with multiple functions., Zimple Kurlawala
Withaferin a synergistically enhances the effects of paclitaxel against lung cancer., Al Hassan Kyakulaga
Prevention and treatment of familial adenomatous polyposis and colorectal cancer by bilberry-derived anthocyanidins., Ashley M. Mudd
Role of MIR-29B-1 and MIR-29A in endocrine-resistant breast cancer., Penn Muluhngwi
The interaction of homoserine lactones and paraoxonase 2 modulates cell death signaling and cell proliferation., Aaron Mackallan Neely
Reversible silencing of spinal neurons unmasks a left-right coordination continuum., Amanda Marie Pocratsky
Novel insight into the liver-lung axis in alcohol-enhanced acute lung injury., Lauren G. Poole
The DLK1-MEG3 locus in malignant cells of proposed primordial germ cell origins., Zachariah Payne Sellers
Revisiting neutrophil responses to toll-like receptor 4 : influence of ligand structures and cellular environments., Shuvasree Sengupta
The role of HIF-1α in intestinal epithelial barrier function in alcoholic liver disease., Tuo Shao
Combating malignant melanoma with the multifaceted soy-dervied peptide lunasin., Christopher Paul Shidal
The comparative cytotoxicity and genotoxicity of hexavalent chromium in humans and sea turtles., Rachel M. Speer
Role of human arylamine n-acetyltransferase 1 in tumorigenesis and cancer biology., Marcus William Stepp
BDNF-TRKB signaling regulates adult taste bud innervation., Tao Tang
Characterization of a mutant oncolytic adenovirus and the role of jnk in enhancing virotherapy., Stephen L. Wechman
Targeting Fas pathway as an effective means of inducing tolerance to pancreatic islets., Kyle Blake Woodward
Circuits for active vision : parallel tectothalamocortical visual pathways in the mouse., Na Zhou
Theses/Dissertations from 2016
Cardiovascular and hematopoietic responses to volatile benzene exposure., Wesley Tyler Abplanalp
Identification of residual descending pathways after human spinal cord injury., Darryn A. Atkinson
Role of phosphodiesterase-4 in alcohol-induced organ injury., Diana Veronica Avila
