This collection includes theses and dissertations from the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please fill out the Electronic Theses & Dissertations form.
Theses/Dissertations from 2012
Polychlorinated biphenyl 153 exacerbates nonalcoholic fatty liver disease in C57BL/6 mice., Banrida Wahlang 1986-
Structure-activity relationship model for estrogen receptor ligands., Huihui Wu 1979-
Theses/Dissertations from 2011
Roles of 5HT1A receptor in CNS neurogenesis and ADAM21 in spinal cord injury., Sheila Ann Arnold 1981-
Roles of VAMP3 in melanoma cell migration and integrin trafficking., Yaman Babi 1981-
Development and evaluation of polymeric implants of curcumin for enhanced chemopreventive activity., Shyam Sunder Bansal
Partial vs. full support of the heart with a continuous-flow left ventricular assist device : implications for myocardial recovery., Carlo Renato G. Bartoli
Profile of systemic treatment with the antiviral lectin Griffithsin in guinea pigs., Christopher Lynn Barton 1976-
Mechanistic insights into copper-induced regression of heart hypertrophy., Katherine Bourcy
Identification and biochemical characterization of the CHLAMYDIA TRACHOMATIS type III secretion chaperone, SLC1, and its role in the translocation of the invasion-associated effector TARP., Amanda J. Brinkworth
Prevention and treatment of lung cancer by green tea polyphenols., Pengxiao Cao
Adenovirus-induced cyclin E activates CDK2 for virus replication., Pei-Hsin Cheng 1983-
Tumor-targeting aptamers for the treatment of prostate cancer., Enid W. Choi
Expression pattern of CD2AP in the intact and collaterally sprouting nervous system., Sarah Elizabeth Claypool Couch 1987-
Histone deacetylase inhibition-mediated cytotoxicity of oligodendrocytes., Toros Ali Dincman 1982-
Reconciliation of IL-1ß loss with TRIF-biased TLR4 signaling by monophosphate lipid A., Chelsea A. Embry
Age-associated changes in innate immunity and their impacts on inflammatory disease., Mehmet Akif Eskan
Effect of complement C5a in tumor progression and the local tumor microenvironment., Lacey Jo Gunn
Characterization of DNA-binding proteins as clinically relevant biomarkers of breast cancer behavior., Traci L. Kruer 1979-
Searching for novel ligands for the cannabinoid and related receptors., Pritesh Prakash Kumar 1986-
Cytotoxicity and cellular response to alpha, beta-unsaturated aldehydes : role of aldehyde dehydrogenases., Ngome Llewellyn Makia
Role of HDACs and SAM in interferon-alpha signaling and epigenetic regulation of anti-HCV gene expression., Stephanie A. Mathews
Structure-based design of inhibitors of CXCR4., Jason Bradley Meier 1980-
Functional analysis of N-acetyltransferase (NAT1*14B and NAT1*10) in complete NATb and NATa mRNA., Lori Michele Millner
Cytokine genetics and expression : implications of an immunogenetic pathogenesis in autism spectrum disorders., Meghan Carey Mott
Mitigating cisplatin resistance in ovarian cancer., Clarisse S. Muenyi
Arsenic-induced developmental changes in the liver and adult cardiovascular disease., Ntube Nini Olive Ngalame
Effects of environmental pollution on endothelial progenitor cells and vascular regeneration., Laura A. Wheat Nissley 1983-
Characterization of the AI-2-dependent quorum sensing pathway in Aggregatibacter actinomycetemcomitans., Elizabeth A. Novak
TRAF6 signaling in skeletal muscle atrophy and regeneration., Pradyut K. Paul
Annonacin in Asimina triloba fruit : implications for neurotoxicity., Lisa Fryman Potts
The effects of a video designed to empower parents to find the time to complete their child's speech and language homework., Lana E. Ridge 1987-
Pharmacists as mid-level healthcare providers and the clinical results of a pharmacist-led diabetes disease management program., Benjamin Maurice Risner 1983-
The role of curcumin in response to BPDE-induced DNA damage in human lung epithelial cells., Erica Nicole Rogers
Sulforaphane prevents acetaminophen-induced hepatic injury in mice., Robin H. Schmidt 1984-
Exploitation of costimulatory SA-4-1BBL in the development of therapeutic cancer vaccines., Abhishek K. Srivastava
DNA polymerase iota promotes G2/M checkpoint activation and genetic stability after UV-induced DNA damage., Lindsey Jay Stallons 1983-
A statin-regulated microRNA represses c-Myc expression and function., Apana Agha L. Takwi 1980-
Pulmonary function and respiratory muscle activation in individuals with chronic spinal cord injury., Daniela Paleville Terson
The effect of tissue damage and inflammation on gene expression in sensory neurons., Sean Anthony Trusty 1984-
Cardiac abnormalities after transaortic constriction are worsened by changing glucose metabolism and benefited by repair of mitochondrial DNA., Jianxun Wang 1969-
Elevation of cardiac glycolysis reduces pyruvate dehydrogenase but increases glucose oxidation., Qianwen Wang
Theses/Dissertations from 2010
Tobacco-induced changes to Porphyromonas gingivalis gene expression, phenotype and host-pathogen interactions., Juhi Bagaitkar
Low-frequency repetitive transcranial magnetic stimulation modulates evoked-gamma power, event-related potentials, and behavior in autism spectrum disorders., Joshua Matthias Baruth
Topology and function of nyctalopin in yeast and in-vitro translation systems., Pasano Pasano Bojang
The role of matrix metalloproteinases induced angiogenesis during transition from compensatory cardiac hypertrophy to cardiac failure : therapeutic effects of hydrogen sulfide., Srikanth Givvimani
Dimensional relationships between the sphenoid sinus, maxillary sinuses and other craniomaxillofacial structures using cone-beam computed tomography analysis., Richard Michael Halpern
Determination of in silico rules for predicting small molecule binding behavior to nucleic acids in vitro., Patrick Andrew Holt
The role of MUC1 splice variants in dry eye and inflammation., Yoannis Imbert-Fernandez
Analysis of candidate plasticity genes in visual cortex., Paul Joseph Kiser 1969-
'Complementary' immune evasion by oral pathogen Porphyromonas gingivalis., Jennifer Lynn Krauss
The role of genetic and environmental oxidative stress factors in prostate cancer., Nicole A. Lavender
Functional effects of CYP1A2, NAT1, and NAT2 genetic variants in nucleotide excision repair-deficient human fibroblasts : implications for toxicological risk from environmental arylamines., Carmine Simone Leggett
Inflammatory cell tumor necrosis factor signaling modulates post-infarction left ventricular remodeling., Robert K. Lewis 1977-
SA-4-1BBL as a modulator of T effector to T regulatory cell conversion., Shravan Madireddi 1980-
Substance P and the tectothalamic pathway., Sean Phillip Masterson 1974-
Curcumin reactivates epigenetically silenced tumor suppressor gene tissue factor pathway inhibitor-2 in hepatocellular carcinoma cells., Akshata Moghe 1983-
Cigarette smoke, DNA damage and repair in human cervical and vaginal cells in vitro and ex vivo., Afsoon Moktar
Ribosome maturation in yeast models of Diamond-Blackfan anemia and Shwachman-Diamond syndrome., Joseph Brady Moore 1981-
Munc13-3 mutation prevents critical period neuronal plasticity in visual cortex., James Geoffrey Morris 1984-
Nyctalopin is required for localization of the TRPM1 channel to the retinal depolarizing bipolar cell dendrites., Jillian Nydam Pearring
Cardiac specific transgenic inhibition of nuclear factor-kappaB (NF-kB) mitigates adverse cardiac remodeling and ameliorates cardiac dysfunction in doxorubicin-induced cardiomyopathy., Santosh Kumar Sanganalmath 1977-
A role for regulatory T cells in gender-biased disease susceptibility to murine lupus., Colleen Tucker
Signal processing in the tectothalamic pathway., Haiyang Wei
Arsenic in drinking water causes gene expression changes in the liver related to inflammation and metabolic dysfunction and accelerates atherosclerosis in ApoE-/-mice, Matthew R. Zajack
Theses/Dissertations from 2009
Mitochondrial targeting of the pro-apoptotic protein Bax : Role of the Bax carboxy-terminal tail., Stephanie Erin Brock 1980-
The role of PKC-epsilon in models of alcohol- and toxin-induced liver disease., J. Phillip Kaiser 1981-
Proactive strategies for children with food refusal., Sara E. Langlois 1981-
Implication of tissue response to ischemia gradient in rabbit ear on chronic wound healing., Abhijit Prakash Mahalingashetty 1985-
Mechanisms mediated by CXCL12 signaling through CXCR4 and CXCR7 in breast cancer., LaSharon Denise Mosley
The role of O-GlcNAc signaling in acute myocardial ischemia., Gladys Afor Ngoh
Feeding difficulties in young children with and without autism., Ashley N. Pugh
The role of glycogen synthase kinase 3-beta in interferon beta biology., Huizhi Wang 1975-
Theses/Dissertations from 2008
Lipid aldehydes are substrates and transcriptional regulators of cytochromes P450., Immaculate Amunom
The role of Hsp90 in PC-12 cell survival., Christina Blume Clark
The role of protein kinase A in hypoxia-induced PC-12 cell death., Cynthia Jayne Miller
The use of the reducing agent N-(2-Mercaptopropionyl)glycine to detoxify oxidized lipids in atherosclerotic lesions., Nason P. Schooler 1974-
Mutagenic and tumor suppressor functions of DNA polymerase iota in mammalian cells., Lindsey Jay Stallons 1983-
Neuropsychiatric features of parkinsonian tauopathies and alpha-synucleinopathies., Megan Rayne Thompson 1985-
A possible role for sPLA2 in oligodendrocyte death and spinal cord injury., William Lee Titsworth
The expression and localization of cytoplasmic polyadenylation element binding proteins in the retina., Xiangping Wang
Theses/Dissertations from 2007
Gene therapy and cellular transplantation : towards a combination strategy for spinal cord injury repair., Ahmed Abdelzaher Abdellatif
Kinematic analysis of treadmill walking in normal and contused mice using the Treadscan system., Jason Beare 1980-
Participation of mouse DNA polymerases iota, eta, and rev1 in translesion synthesis of carcinogen induced DNA adducts and carcinogenesis., Chad Aaron Dumstorf 1977-
Effects of direct ATP delivery to ischemic skeletal muscle., Federico V. Grossi 1974-
Non-redundant and critical roles for leukotriene B4 receptors BLT1 and BLT2 in mouse models of inflammatory arthritis., Steven Mathis 1979-
Regulation of nuclear respiratory factor-1 expression by 17beta-estradiol : a new mechanism for coordinating mitochondrial gene expression., Kathleen AnnMarie Mattingly 1979-
The changes of fructos-2,6-bisphosphate level in transgenic mice causing cardiomyopathy., Jianxun Wang 1969-
Therapeutic targeting of tumor associated macrophages., Stephanie Kaye Watkins 1981-
Theses/Dissertations from 2006
Molecular pathogenesis of Legionella longbeachae., Rexford Asare 1972-
Mechanism of 4-Hydroxynonenal induced toxicity in Jurkat CD4+ T lymphocytes., Wei Yuan Chang
Mechanistic studies of guanine-rich oligonucleotides., Allicia C. Girvan 1978-
Regulation of angiogenic factors by pituitary tumor transforming gene (PTTG) in tumorigenesis., Mohammad Tariq Malik
Theses/Dissertations from 2005
Defining the mechanisms of neutrophil exocytosis using proteomic techniques., George Lominadze 1978-
Sex-based differences in regulatory T cells., Lum Doreen Nebane-Ambe 1975-
Role of inducible nitric oxide synthase and p-selectin in platelet-arteriolar wall adhesion and associated arteriolar constriction during lung reperfusion., Alexander V. Ovechkin 1957-
Investigations of N-acetyltransferases in human hepatocytes and rat models., Jason Matthew Walraven
Induction of lineage and differentiation of adult human neuroepithelial progenitors in vitro., Xiaodong Zhang 1968-
