This collection includes theses and dissertations from the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please fill out the Electronic Theses & Dissertations form.
Theses/Dissertations from 2018
Canonical nuclear factor-κB signaling in satellite stem cell homeostasis and function., Alex R. Straughn
Exercise preconditioning and TFAM overexpression diminish skeletal muscle atrophy., Nicholas Todd Theilen
Particulate hexavalent chromium does not induce centrosome amplification in sperm whale and bowhead whale cells., Jennifer Haruka Toyoda
Characterizing the virulence factor YapE in Yersinia pestis., Tiva Templeton VanCleave
Functional consequence of PSAT1 association on PKM2's inherent enzymatic activity., Alexis Avidan Vega
The involvement of epithelial cells in arenavirus-induced pathogenesis., Nikole Leslie Margaret Warner
Tissue engineered micro and macrovasculature utilizing stromal vascular fraction., Joseph Samir Zakhari
Theses/Dissertations from 2017
MiRNA expression changes in arsenic-induced skin cancer in vitro and in vivo., Laila Al-Eryani
Characterization of Filifactor alocis and its immune evasion strategies employed against human neutrophils., Cortney Linn Armstrong
Enhancing cell therapy for ischemic cardiomyopathy., Michael J. Book
Neural coding of natural and synthetic speech., Allison Brown
PCB-associated steatohepatitis and the role of nuclear receptors., Heather Brooke Clair
Spinal cord injury induced cardiac decline and the limitations of exercise., Kathryn Michele DeVeau
Spontaneous vocal matching in mothers and their hearing impaired infants with cochlear implants : a quantitative analysis., Lydia Doggett
The effects of moderate alcohol consumption and inflammation on the hepatic matrisome and the renal cortex proteome., Christine E. Dolin
Sphingolipids in models of kidney disease and injury., Tess V. Dupre
Metabolic regulation of myocardial adaptation to exercise., Andrew Alan Gibb
Age-related host factors regulate lung cancer progression., John Caleb Greenwell
Targeting the glucose metabolism of myeloid-derived suppressor cells (MDSCs) to stimulate cancer immunity., Jaspreet Grewal
Targeting the major regulator of mitosis., J. Mason Hoffman
Diffusion-weighted magnetic resonance imaging in diagnosing graft dysfunction : a non-invasive alternative to renal biopsy., Elizabeth Marie Hollis
Identifying the signaling mechanisms of EGFR-mediated apoptosis., Nicole Marion Jackson
Advances in tumor-targeted therapy using nanomedicine., Divya Karukonda
Stretching adversely modulates locomotor capacity following spinal cord injury via activation of nociceptive afferents., Anastasia V. Keller
Mitochondrial Transcription Factor A's role in heart failure., George H. Kunkel
UBQLN1 : a multi-domain protein with multiple functions., Zimple Kurlawala
Withaferin a synergistically enhances the effects of paclitaxel against lung cancer., Al Hassan Kyakulaga
Prevention and treatment of familial adenomatous polyposis and colorectal cancer by bilberry-derived anthocyanidins., Ashley M. Mudd
Role of MIR-29B-1 and MIR-29A in endocrine-resistant breast cancer., Penn Muluhngwi
The interaction of homoserine lactones and paraoxonase 2 modulates cell death signaling and cell proliferation., Aaron Mackallan Neely
Reversible silencing of spinal neurons unmasks a left-right coordination continuum., Amanda Marie Pocratsky
Novel insight into the liver-lung axis in alcohol-enhanced acute lung injury., Lauren G. Poole
The DLK1-MEG3 locus in malignant cells of proposed primordial germ cell origins., Zachariah Payne Sellers
Revisiting neutrophil responses to toll-like receptor 4 : influence of ligand structures and cellular environments., Shuvasree Sengupta
The role of HIF-1α in intestinal epithelial barrier function in alcoholic liver disease., Tuo Shao
Combating malignant melanoma with the multifaceted soy-dervied peptide lunasin., Christopher Paul Shidal
The comparative cytotoxicity and genotoxicity of hexavalent chromium in humans and sea turtles., Rachel M. Speer
Role of human arylamine n-acetyltransferase 1 in tumorigenesis and cancer biology., Marcus William Stepp
BDNF-TRKB signaling regulates adult taste bud innervation., Tao Tang
Characterization of a mutant oncolytic adenovirus and the role of jnk in enhancing virotherapy., Stephen L. Wechman
Targeting Fas pathway as an effective means of inducing tolerance to pancreatic islets., Kyle Blake Woodward
Circuits for active vision : parallel tectothalamocortical visual pathways in the mouse., Na Zhou
Theses/Dissertations from 2016
Cardiovascular and hematopoietic responses to volatile benzene exposure., Wesley Tyler Abplanalp
Identification of residual descending pathways after human spinal cord injury., Darryn A. Atkinson
Role of phosphodiesterase-4 in alcohol-induced organ injury., Diana Veronica Avila
Immune monitoring in recipients of combined living donor kidney and hematopoietic stem/facilitating cell transplants., Mark DeWayne Badder
SA-4-1BBL as a modulator of innate, adaptive, and regulatory immunity : implications for cancer prevention and treatment., Hampartsoum Barsoumian
Establishing a clinically relevant mouse model of human AML to test novel transmethylation inhibitors., Aditya Barve
Carnosine, a therapeutic potential for critical limb ischemic., Adjoa Agyemang Boakye
The role of the MiR-200 family on the tumor suppressor RASSF2 and the effect on MAPK pathway activity in colorectal cancer., Jane V. Carter
Acrolein is a critical mediator of alcohol-induced liver and intestinal injury in alcoholic liver disease., Wei-Yang (Jeremy) Chen
Identification of host factors required for Yersinia pestis macrophage intracellular survival and their impact on vacuole maturation, acidification and trafficking., Michael Graylin Connor
The role of O-GlcNAcase during heart failure., Sujith Dassanayaka
Impact of epigallocatechin-3-gallate (EGCG), a broad-spectrum anti-inflammatory, in controlling intestinal factors contributing to inflammatory bowel disease., Gerald Wayne Dryden, Jr.
Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-mediated hypertension., Anastasia Familtseva
Air pollution, pulmonary oxidative stress, and the endothelin system in the development of cardiovascular injury., Jordan B. Finch
Microbiota activated CD103+ DCS stemming from oral microbiota adaptation specifically drive γδT17 proliferation and activation., Christopher Jay Fleming
In vivo monitoring of therapeutic efficacy and virulence profile by bioluminescent Klebsiella pneumoniae., Ramy Ameen Fodah
The role and regulation of inhibitor of Kappa B Kinase in the impaired monocyte response., Norman James Galbraith
Glutathione s-transferase p in glucose homeostasis in mice., Shubha Ghosh Dastidar
Isolation of EGFR-containing early endosomes., Julie A. Gosney
Characterization of the role of the Burkholderia pseudomallei type 3 secretion system using in vivo imaging., Maria Gabriela Gutierrez
The role of the nucleolus in neurodegeneration., Justin Lauren Hallgren
Role of microRNA-21 in atherogenesis., Rihab Hamed-Berair
Evaluating cardiovascular dysfunction during increased activity and exercise rehabilitation following incomplete thoracic spinal cord injury in the adult rat., Kathryn A. Harman
Pro-inflammatory cytokines promote viral replication and cell cycle mediators in arenavirus-induced hepatitis., Gretchen E. Holz
MicroRNA-186 and metastatic prostate cancer., Dominique Zilpha Jones
Molecular characterization of human papillomavirus in head and neck tumors., Sujita Khanal
Modulation of cardiac Kv currents by Kvbeta2 and pyridine nucleotides., Peter Joseph Kilfoil
ABIN1 in the pathogenesis of Glomerulonephritis and the novel polocyte-neutrophil proinflammatory axis., Erik Anderson Korte
Effects of neonatal capsaicin on formalin-induced ATF3 expression in the adult rat., Sarah Krupp
Vinyl chloride-diet interactions in liver disease : potential roles of autophagy and energy management., Anna L. Lang
Congenic and functional analysis of rat mammary cancer susceptibility., Saasha Le
TNF-like weak inducer of apoptosis (TWEAK) : not so weak after all., Joseph Dekward McMillan IV
A systems biology approach identifies a gene regulatory network in parotid acinar cell differentiation., Melissa Ann Metzler
Modulation of cell death signaling and cell proliferation by the interaction of homoserine lactones and Paraoxonase 2., Aaron Mackallan Neely
The influence of miR-99a on mTOR signaling regulation in colorectal cancer cell lines., Jonathan Rice
Developing a more clinically-relevant mouse model of cisplatin-induced nephrotoxicity., Cierra N. Sharp
The discovery of a novel, Ras-mediated NORE1A/PMLIV tumor suppressor complex., Jessica Mezzanotte Sharpe
The role of nicotine, a7 nicotinic acetylcholine receptors and extracellular matrix remodeling in pulmonary fibrosis., Glenn Ward Vicary
The effects of direct peritoneal resuscitation on leukocyte infiltration after acute brain death., Jessica Lee Weaver
Theses/Dissertations from 2015
Immunomodulation of myeloid-derived suppressor cells by particulate b-glucan in cancer., Sabrin Husein Albeituni
Characterizing the neuropeptide pathways between the forebrain and the pons., Ali Al-Magableh
Promoting differentiation and survival of human c-kit+ cardiac progenitor cells ex vivo., Tareq Al-Maqtari
A plant-made cholera toxin B subunit enhances mucosal wound healing and protects against ulcerative colitis and colon cancer., Keegan J Baldauf
Regulation of the retinoblastoma tumor suppressor by the novel Ras effector NORE1A., Thibaut François Barnoud
Critical insights into the pathogenesis of clinical isolates of pandemic influenza A(H1N1) 2009 virus in mouse and ferret models., Jeremy V. Camp 1980-
Metabolomics of transformed MDA-MB-231 cell lines expressing different levels of human arylamine N-acetyltransferase 1 (NAT1)., Samantha Marie Carlisle
Chemoattractant receptors BLT1 and CXCR3 regulate anti-tumor immunity by facilitating CD8+ T cell migration to tumors., Zinal S. Chheda
Cardiovascular regulation and effects of respiratory motor training in patients with chronic spinal cord injury., Bonnie Legg Ditterline
Mechanisms and intervention strategies for alcohol and HIV-antiretroviral therapy-induced liver injury., Hridgandh Donde
Suramin protects from cisplatin-induced acute kidney injury., Tess Dupre
Early host response and immune signaling to 2009 pandemic influenza A (H1N1) viruses in primary cell culture models., Rachael Lask Gerlach
Exploring the roles of host and tumor cell α4 and α7 nicotinic acetylcholine receptors in lung cancer., John Caleb Greenwell
