This collection includes theses and dissertations from the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please fill out the Electronic Theses & Dissertations form.
Theses/Dissertations from 2014
Craniodental anatomy of a new late cretaceous multituberculate mammal from Udan Sayr, Mongolia., Amir Subhash Sheth
Lunasin reduces the melanoma stem cell population in vitro and inhibits tumor proliferation in vivo., Christopher Paul Shidal
Preventive effect of non-mitogenic acidic fibroblast growth factor on diabetes-induced testicular cell death., Melissa Skibba 1990-
Building a metabolic bridge between glycolysis and sphingolipid biosynthesis : implications in cancer., Morgan L. Stathem
Inducible tumor difference between rapid and slow rat Nat2 congenic Fischer 344 rats administered methyl-nitrosourea., Marcus W. Stepp
Effects of passive immobilization on locomotor recovery after spinal cord injury in adult rats., Kelsey Lee Stipp
Evaluating the effects of aroclor 1260 in non-alcoholic fatty liver disease : the role of xenobiotic receptors., Banrida Wahlang
Mechanisms of action and co-optive evolution for hypervariable courtship pheromones in plethodontid salamanders., Wilburn Beau Wilburn
Inflammation-resolving lipid mediators promote revascularization to enhance wound healing., Michael Jingyuan Zhang
Regulation of macrophage inflammatory signaling pathways by AMP-activated protein kinase., Yanfang Zhu
Theses/Dissertations from 2013
Probing the anti-cancer mechanism of selenite : a metabolic approach., Alex Belshoff
Mast cell-T cell interactions in inflammatory chemokine mediated immune surveillance of intestinal cancer., Sobha R. Bodduluri
AMP-activated protein kinase regulation of myeloid antigen presenting cell activity., Kelly Casey Carroll
Cyclin E induction and oncolytic replication of E1b-deleted adenoviruses., Pei-Hsin Cheng
Genetic mapping and mechanism of action of rat mammary carcinoma susceptibility quantitative trait locus Mcs1b., Aaron D. denDekker
Role of ethanol as a cofactor in HAART induced hepatic steatosis and injury., Hridgandh Donde
Enhanced penetration of lipid functionalized nanoparticles in 3D cell cultures., Christopher Gene England 1988-
Synapses, spines, zinc and pathology of Alzheimer's disease., Dmitry Familtsev 1985-
The role of neurotrophin receptors in taste development., Da Fei
The retina-prosthesis interface in two rat models of retinitis pigmentosa and functional changes associated with photoreceptor loss., James William Fransen
Effects of telemetry EMG implants on hindlimb locomotor recovery in thoracic spinal contused rats., Matthew L. Hamilton
Molecular bases of inherited bone marrow failures : Shwachman-Diamond syndrome and Diamond Blackfan anemia., Adrianna Lee Henson 1983-
Gene expression analysis of neurotrophins, Trk receptors, and associated regulatory molecules after contusive spinal cord injury., Matthew Tyler Hougland 1982-
Post-mortem analysis of cortical thickness and neuronal morphometry in autism., Shweta Sunil Kamat
Audiovisual sensory processing in autism spectrum condition., Ryan Mikel Burdette Kiser
6-phosphofructo-2-kinase inhibition induces autophagy as a survival mechanism., Alden Klarer
Preclinical safety assessment of Griffithsin-based vaginal microbicides., Amanda Lasnik
COUP-TFII and its interacting proteins in breast cancer and endocrine resistance., Lacey Morgan Litchfield
Using the virtual world of Second Life to teach cultural competence for health science professional students., Ashley Mack 1986-
Constructing the rod bipolar cell signalplex using animal models of retinal dysfunction., Thomas Andrew Ray 1986-
Olanzapine-induced liver injury : direct metabolic effects, exacerbation by high-fat diet, and protection with sulforaphane., Robin H. Schmidt 1984-
The role of a7 nicotine acetylcholine receptors in lung injury and repair., Glenn Vicary
PACAP : a novel neuropeptide for pituitary gonadotroph maturation, function and regulation., Rongqiang Yang
The involvement of beta-catenin in the inflammatory response leading to autoimmune diabetes development., Arin Lee Zirnheld
Theses/Dissertations from 2012
Approaches in the treatment of Parkinson's disease : a focus on stem cell-based therapies., Tareq Al-maqtari 1979-
Acetaldehyde dehydrogenase 2 (ALDH2) activation protects hepatocytes from mitochondrial damage and death caused by 4-hydroxynonenal., Keegan J. Baldauf 1982-
Pivotal role of Interleukin-10 on microRNA-155 expression in regulation of the monocyte response in hypothermia., Adrian Theophil Billeter 1984-
The dynamic equilibrium of human telomeric G-quadruplexes., Robert Buscaglia
Gain and loss of functional locomotor recovery following contusive spinal cord injury in the adult rat., Krista Layne Caudle
The role of endogenous Bcl-xL in regulation of apoptotic signaling pathways., Colins Ogwandi Eno 1982-
Idiopathic pulmonary fibrosis : diagnosis, management, and the search for a cure., Daniel Fioret
Development of pituitary tumor-transforming gene (PTTG) transgenic mice for the treatment of ovarian cancer., Miranda Y. Fong 1982-
Role of human arylamine N-acetyltransferase in carcinogen metabolism and human breast cancer progression., Carmine Simone Leggett
Co-option and adaptation of novel gene duplications for pheromone activity in a dusky salamander., Kari Anne Leichty 1987-
Dysregulation of microRNA expression in acquired endocrine-resistant breast cancer., Tissa Thomas Manavalan
Integrin inhibitor cycloRGDfV blunts enhanced LPS-induced liver injury caused by ethanol in mice., Veronica L. Massey
Blockade of CXCR4 inhibits Porphyromonas gingivalis colonization in vivo and subsequent periodontal bone loss., Megan L. Mc Intosh
Regulation of vascular smooth muscle cell phenotype., Joshua Kuimeta Salabei
The regulation of RNA Polymerase I-mediated transcription in forebrain neurons., Scott Carl Smith
Hyperhomocysteinemia alters sinoatrial and atrioventricular nodal function : role of the cardiac NMDA receptor., Chirag V. Soni
Expression of adipocyte/macrophage fatty acid binding protein promotes tumor growth and metastasis., Ashley Simone Triplett
Polychlorinated biphenyl 153 exacerbates nonalcoholic fatty liver disease in C57BL/6 mice., Banrida Wahlang 1986-
Structure-activity relationship model for estrogen receptor ligands., Huihui Wu 1979-
Theses/Dissertations from 2011
Roles of 5HT1A receptor in CNS neurogenesis and ADAM21 in spinal cord injury., Sheila Ann Arnold 1981-
Roles of VAMP3 in melanoma cell migration and integrin trafficking., Yaman Babi 1981-
Development and evaluation of polymeric implants of curcumin for enhanced chemopreventive activity., Shyam Sunder Bansal
Partial vs. full support of the heart with a continuous-flow left ventricular assist device : implications for myocardial recovery., Carlo Renato G. Bartoli
Profile of systemic treatment with the antiviral lectin Griffithsin in guinea pigs., Christopher Lynn Barton 1976-
Mechanistic insights into copper-induced regression of heart hypertrophy., Katherine Bourcy
Identification and biochemical characterization of the CHLAMYDIA TRACHOMATIS type III secretion chaperone, SLC1, and its role in the translocation of the invasion-associated effector TARP., Amanda J. Brinkworth
Prevention and treatment of lung cancer by green tea polyphenols., Pengxiao Cao
Adenovirus-induced cyclin E activates CDK2 for virus replication., Pei-Hsin Cheng 1983-
Tumor-targeting aptamers for the treatment of prostate cancer., Enid W. Choi
Expression pattern of CD2AP in the intact and collaterally sprouting nervous system., Sarah Elizabeth Claypool Couch 1987-
Histone deacetylase inhibition-mediated cytotoxicity of oligodendrocytes., Toros Ali Dincman 1982-
Reconciliation of IL-1ß loss with TRIF-biased TLR4 signaling by monophosphate lipid A., Chelsea A. Embry
Age-associated changes in innate immunity and their impacts on inflammatory disease., Mehmet Akif Eskan
Effect of complement C5a in tumor progression and the local tumor microenvironment., Lacey Jo Gunn
Characterization of DNA-binding proteins as clinically relevant biomarkers of breast cancer behavior., Traci L. Kruer 1979-
Searching for novel ligands for the cannabinoid and related receptors., Pritesh Prakash Kumar 1986-
Cytotoxicity and cellular response to alpha, beta-unsaturated aldehydes : role of aldehyde dehydrogenases., Ngome Llewellyn Makia
Role of HDACs and SAM in interferon-alpha signaling and epigenetic regulation of anti-HCV gene expression., Stephanie A. Mathews
Structure-based design of inhibitors of CXCR4., Jason Bradley Meier 1980-
Functional analysis of N-acetyltransferase (NAT1*14B and NAT1*10) in complete NATb and NATa mRNA., Lori Michele Millner
Cytokine genetics and expression : implications of an immunogenetic pathogenesis in autism spectrum disorders., Meghan Carey Mott
Mitigating cisplatin resistance in ovarian cancer., Clarisse S. Muenyi
Arsenic-induced developmental changes in the liver and adult cardiovascular disease., Ntube Nini Olive Ngalame
Effects of environmental pollution on endothelial progenitor cells and vascular regeneration., Laura A. Wheat Nissley 1983-
Characterization of the AI-2-dependent quorum sensing pathway in Aggregatibacter actinomycetemcomitans., Elizabeth A. Novak
TRAF6 signaling in skeletal muscle atrophy and regeneration., Pradyut K. Paul
Annonacin in Asimina triloba fruit : implications for neurotoxicity., Lisa Fryman Potts
The effects of a video designed to empower parents to find the time to complete their child's speech and language homework., Lana E. Ridge 1987-
Pharmacists as mid-level healthcare providers and the clinical results of a pharmacist-led diabetes disease management program., Benjamin Maurice Risner 1983-
The role of curcumin in response to BPDE-induced DNA damage in human lung epithelial cells., Erica Nicole Rogers
Sulforaphane prevents acetaminophen-induced hepatic injury in mice., Robin H. Schmidt 1984-
Exploitation of costimulatory SA-4-1BBL in the development of therapeutic cancer vaccines., Abhishek K. Srivastava
DNA polymerase iota promotes G2/M checkpoint activation and genetic stability after UV-induced DNA damage., Lindsey Jay Stallons 1983-
A statin-regulated microRNA represses c-Myc expression and function., Apana Agha L. Takwi 1980-
Pulmonary function and respiratory muscle activation in individuals with chronic spinal cord injury., Daniela Paleville Terson
The effect of tissue damage and inflammation on gene expression in sensory neurons., Sean Anthony Trusty 1984-
Cardiac abnormalities after transaortic constriction are worsened by changing glucose metabolism and benefited by repair of mitochondrial DNA., Jianxun Wang 1969-
Elevation of cardiac glycolysis reduces pyruvate dehydrogenase but increases glucose oxidation., Qianwen Wang
Theses/Dissertations from 2010
Tobacco-induced changes to Porphyromonas gingivalis gene expression, phenotype and host-pathogen interactions., Juhi Bagaitkar
Low-frequency repetitive transcranial magnetic stimulation modulates evoked-gamma power, event-related potentials, and behavior in autism spectrum disorders., Joshua Matthias Baruth
Topology and function of nyctalopin in yeast and in-vitro translation systems., Pasano Pasano Bojang
The role of matrix metalloproteinases induced angiogenesis during transition from compensatory cardiac hypertrophy to cardiac failure : therapeutic effects of hydrogen sulfide., Srikanth Givvimani
Dimensional relationships between the sphenoid sinus, maxillary sinuses and other craniomaxillofacial structures using cone-beam computed tomography analysis., Richard Michael Halpern
Determination of in silico rules for predicting small molecule binding behavior to nucleic acids in vitro., Patrick Andrew Holt
