This collection includes theses and dissertations from the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please see: http://ir.library.louisville.edu/about.html.

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Theses/Dissertations from 2010

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The role of MUC1 splice variants in dry eye and inflammation., Yoannis Imbert-Fernandez

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Analysis of candidate plasticity genes in visual cortex., Paul Joseph Kiser 1969-

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'Complementary' immune evasion by oral pathogen Porphyromonas gingivalis., Jennifer Lynn Krauss

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The role of genetic and environmental oxidative stress factors in prostate cancer., Nicole A. Lavender

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Functional effects of CYP1A2, NAT1, and NAT2 genetic variants in nucleotide excision repair-deficient human fibroblasts : implications for toxicological risk from environmental arylamines., Carmine Simone Leggett

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Inflammatory cell tumor necrosis factor signaling modulates post-infarction left ventricular remodeling., Robert K. Lewis 1977-

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SA-4-1BBL as a modulator of T effector to T regulatory cell conversion., Shravan Madireddi 1980-

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Substance P and the tectothalamic pathway., Sean Phillip Masterson 1974-

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Curcumin reactivates epigenetically silenced tumor suppressor gene tissue factor pathway inhibitor-2 in hepatocellular carcinoma cells., Akshata Moghe 1983-

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Cigarette smoke, DNA damage and repair in human cervical and vaginal cells in vitro and ex vivo., Afsoon Moktar

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Ribosome maturation in yeast models of Diamond-Blackfan anemia and Shwachman-Diamond syndrome., Joseph Brady Moore 1981-

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Munc13-3 mutation prevents critical period neuronal plasticity in visual cortex., James Geoffrey Morris 1984-

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Nyctalopin is required for localization of the TRPM1 channel to the retinal depolarizing bipolar cell dendrites., Jillian Nydam Pearring

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Cardiac specific transgenic inhibition of nuclear factor-kappaB (NF-kB) mitigates adverse cardiac remodeling and ameliorates cardiac dysfunction in doxorubicin-induced cardiomyopathy., Santosh Kumar Sanganalmath 1977-

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A role for regulatory T cells in gender-biased disease susceptibility to murine lupus., Colleen Tucker

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Signal processing in the tectothalamic pathway., Haiyang Wei

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Adriamycin nephrotoxicity is reduced by metallothionein over-expression and kidney gene expression is modified by diabetes in the OVE26 diabetic model., Lu Yang

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Arsenic in drinking water causes gene expression changes in the liver related to inflammation and metabolic dysfunction and accelerates atherosclerosis in ApoE-/-mice, Matthew R. Zajack

Theses/Dissertations from 2009

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Mitochondrial targeting of the pro-apoptotic protein Bax : Role of the Bax carboxy-terminal tail., Stephanie Erin Brock 1980-

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The role of PKC-epsilon in models of alcohol- and toxin-induced liver disease., J. Phillip Kaiser 1981-

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Proactive strategies for children with food refusal., Sara E. Langlois 1981-

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Implication of tissue response to ischemia gradient in rabbit ear on chronic wound healing., Abhijit Prakash Mahalingashetty 1985-

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Mechanisms mediated by CXCL12 signaling through CXCR4 and CXCR7 in breast cancer., LaSharon Denise Mosley

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The role of O-GlcNAc signaling in acute myocardial ischemia., Gladys Afor Ngoh

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Feeding difficulties in young children with and without autism., Ashley N. Pugh

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The role of glycogen synthase kinase 3-beta in interferon beta biology., Huizhi Wang 1975-

Theses/Dissertations from 2008

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Lipid aldehydes are substrates and transcriptional regulators of cytochromes P450., Immaculate Amunom

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The role of Hsp90 in PC-12 cell survival., Christina Blume Clark

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The role of protein kinase A in hypoxia-induced PC-12 cell death., Cynthia Jayne Miller

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The use of the reducing agent N-(2-Mercaptopropionyl)glycine to detoxify oxidized lipids in atherosclerotic lesions., Nason P. Schooler 1974-

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Mutagenic and tumor suppressor functions of DNA polymerase iota in mammalian cells., Lindsey Jay Stallons 1983-

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Neuropsychiatric features of parkinsonian tauopathies and alpha-synucleinopathies., Megan Rayne Thompson 1985-

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A possible role for sPLA2 in oligodendrocyte death and spinal cord injury., William Lee Titsworth

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The expression and localization of cytoplasmic polyadenylation element binding proteins in the retina., Xiangping Wang

Theses/Dissertations from 2007

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Gene therapy and cellular transplantation : towards a combination strategy for spinal cord injury repair., Ahmed Abdelzaher Abdellatif

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Kinematic analysis of treadmill walking in normal and contused mice using the Treadscan system., Jason Beare 1980-

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Participation of mouse DNA polymerases iota, eta, and rev1 in translesion synthesis of carcinogen induced DNA adducts and carcinogenesis., Chad Aaron Dumstorf 1977-

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Effects of direct ATP delivery to ischemic skeletal muscle., Federico V. Grossi 1974-

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Non-redundant and critical roles for leukotriene B4 receptors BLT1 and BLT2 in mouse models of inflammatory arthritis., Steven Mathis 1979-

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Regulation of nuclear respiratory factor-1 expression by 17beta-estradiol : a new mechanism for coordinating mitochondrial gene expression., Kathleen AnnMarie Mattingly 1979-

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Molecular interactions between the Wilms' tumor transcription factor and the aryl hydrocarbon receptor during nephrogenesis and its impact on fetal programming of renal disease., Adrian Nanez

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The changes of fructos-2,6-bisphosphate level in transgenic mice causing cardiomyopathy., Jianxun Wang 1969-

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Therapeutic targeting of tumor associated macrophages., Stephanie Kaye Watkins 1981-

Theses/Dissertations from 2006

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Molecular pathogenesis of Legionella longbeachae., Rexford Asare 1972-

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Mechanism of 4-Hydroxynonenal induced toxicity in Jurkat CD4+ T lymphocytes., Wei Yuan Chang

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Mechanistic studies of guanine-rich oligonucleotides., Allicia C. Girvan 1978-

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Regulation of angiogenic factors by pituitary tumor transforming gene (PTTG) in tumorigenesis., Mohammad Tariq Malik

Theses/Dissertations from 2005

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Defining the mechanisms of neutrophil exocytosis using proteomic techniques., George Lominadze 1978-

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Sex-based differences in regulatory T cells., Lum Doreen Nebane-Ambe 1975-

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Role of inducible nitric oxide synthase and p-selectin in platelet-arteriolar wall adhesion and associated arteriolar constriction during lung reperfusion., Alexander V. Ovechkin 1957-

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Investigations of N-acetyltransferases in human hepatocytes and rat models., Jason Matthew Walraven

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Induction of lineage and differentiation of adult human neuroepithelial progenitors in vitro., Xiaodong Zhang 1968-

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Explore the murine cardiac 20S proteasomes : molecular composition and regulation., Chenggong Zong

Theses/Dissertations from 2004

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The role of the toll-like receptor pathway in susceptibility to inflammatory bowel disease., Nigel Crawford 1974-

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The transcriptional repressor protein growth factor independence-1B in T lymphopoiesis., Loretta L. Doan

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The role of nuclear factors of activated T-cells (NFAT) in neuronal death., Agata M. Habas 1976-

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The roles of pancreatic beta cell antioxidants in islet transplantation and type 1 diabetes., Xiaoyan Li

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DHEA action is mediated by multiple receptors and metabolites., Kristy K. Michael Miller

Theses/Dissertations from 2003

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Regulation of Na,K-Atpase activity by tyrosine phosphorylation in lens cells., Larry Darko Bozulic 1974-

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Studies of the effects of pancreatic beta cell antioxidant transgenes on experimental models of diabetes., Hainan Chen

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Oxygen toxicity and mitochondrial metabolism., Jian Li 1974-

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Functional proteomic analysis of the myocardial PKCepsilon subproteome PKCepsilon-AKT-eNOS signaling modules and during., Jun Zhang

Theses/Dissertations from 2002

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Metallothionein overexpression prolongs grafts survival in the early phase of pancreatic islet transplantation., Xiaoyan Li

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Proteomics and morphology demonstrate mitochondrial changes in diabetic cardiomyopathy., Xia Shen 1976-

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Structure-function studies of the vaccinia virus complement control protein., Scott Alan Smith

Theses/Dissertations from 2001

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Characterization of secA-sod operon in Borrellia burgdorferi., Tonya Lynn Nichols

Theses/Dissertations from 1948

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A biochemical investigation of cirrhosis., Mary Frank Beattie

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Methemoglobin., Herbert Friedman

Theses/Dissertations from 1947

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Studies on synthesis by enzymatic catalysis., Charles Henry Wabnitz 1916-2004

Theses/Dissertations from 1945

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Studies on spinal anesthesia., Frederic E. Shaffer

Theses/Dissertations from 1943

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The incidence of human infestation with Trichinella spiralis as revealed by the examination of 570 diaphragms at the Louisville General Hospital, Louisville, Kentucky., Letitia S. Kimsey

Theses/Dissertations from 1940

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The effect of distention on blood flow through the intestine., Jack Chumley

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The effect of hypophysectomy on gastric motility in the dog., Edmund A. Smolik

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A comparison of various sizes of inverted vials used in Durham fermentation tubes., Blanche Mae Welsh

Theses/Dissertations from 1938

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The muscular activity of the small intestine during acute obstruction., Rudolph F. Antoncic

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A cytological study of the ciliated epithelium of Nucula castrensis Hinds., Dorothy Blumer

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A study of the relationship between blood flow and limb volume in the hind limb of the dog., J. P. Holt

Theses/Dissertations from 1937

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The effect of splenectomy on the differential cell count of the anterior pituitary in relation to post-splenectomy changes in the blood picture of the dog., Herbert J. Brinker

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The effect of drugs on experimental renal hypertension in the dog., J. J. Prusmack

Theses/Dissertations from 1936

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The effect of experimental liver damage on the blood picture of the dog., H. D. Bruner

Theses/Dissertations from 1934

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The role of membranes and phase boundaries in generating electric currents in living tissues., Norman E. Epstein

Theses/Dissertations from 1932

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The cause of vascular sclerosis in essential hypertension and related phenomena, Claude W. Chappell

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A study of the movements of the heart and their relationship to the filling of the auricles., John H. Rompf

Theses/Dissertations from 1931

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The influence of the brain upon the liver as a blood concentrating organ in fever., Benjamin F. Aydelotte 1899-1956

Theses/Dissertations from 1930

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Effects of thermal influences upon the pons and medulla and upon the mid brain and diencephalon after ligation of the basilar artery., Franklin Jelsma

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The fate of water lost from the blood in cocaine fever and the relation of this water to the febrile process., Hubert T. Marshall