This collection includes theses and dissertations from the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please fill out the Electronic Theses & Dissertations form.
Theses/Dissertations from 2015
Characterization of the innate response to the RagB protein of Porphyromonas gingivalis., Justin Hutcherson
The regulation and mechanisms of EGFR-mediated apoptosis in MDA-MB-468 cells., Nicole Marion Jackson
Combination treatment with conjugated linoleic acid and nitrite protects against myocaridal infarction., Natia Qipshidze Kelm
Searching for novel ligands for the cannabinoid and related receptors., Pritesh Prakash Kumar
Regulation of receptor tyrosine kinases by Ubiquilin1., Zimple Kurlawala
The Ras effector NORE1A forms a tumor suppressor complex with BRCA1., Nicholas C Nelson
Identifying Hepatocellular Carcinoma (HCC) cells with cancer stem cell-like properties., Harshulkumar M. Pandit
Development of a vascularized, induced pluripotent stem cell-derived liver-tissue mimic for therapeutic applications., Venkat Madhav Ramakrishnan
Coordinate regulation of the WNT and Hippo pathways by the novel Ras effector NORE1A., Marvin Lee Schmidt Jr.
Role of c-Kit in the growth, migration and differentiation of human cardiac progenitor cells., Bathri Narayan Vajravelu
Improved oncolytic virotherapy by increasing virus spread within tumors., Stephen Wechman
Functional characterization of Aggregatibacter actinomycetemcomitans QSEBC : a bacterial adrengeric receptor and global regulator of virulence., Whitney Weigel
Exercise mitigates the effects of hyperhomocysteinemia on adverse skeletal muscle remodeling., Lee Winchester
Circulating angiogenic stem cells in diabetes., Nagma Zafar
Theses/Dissertations from 2014
The role of pesticides in non-alcoholic fatty liver disease (NAFLD)., Laila Al-Eryani 1986-
Pathogenic role of phosphodiesterase 4 (pde4) in the development of alcohol induced hepatic steatosis., Diana Veronica Avila
MiRNA-21 has anti-inflammatory effects in the macrophage response to peritonitis., Rebecca Elise Barnett
Evaluation of the safety and pharmacokinetic profile of the broad spectrum antiviral lectin Griffithsin., Christopher Lynn Barton
Augmentation of Ras-induced cell transformation : a new role for miR-200a in malignancy., Lindsey Erin Becker
Modulation of host polyubiquitination by the ankb f-box protein of Legionella pneumophila., William M. Bruckert
Pathogenic role of acrolein in alcoholic liver disease., Wei-Yang (Jeremy) Chen
Enzyme kinetics : 6-phosphofructo-2-kinase/2,6-bisphosphatase., Jennifer Clark
SA-4-1BBL as a platform to develop adjuvant systems for prophylactic and therapeutic vaccines., Gunes Dinc 1984-
Study of novel nanoparticle transport and drug release for cancer treatment., Christopher Gene England 1988-
Neurodegeneration-associated instability of ribosomal DNA., Justin Lauren Hallgren 1981-
The effect of spinal cord injury on vagal afferents., April N. Herrity
Signaling mechanisms in regenerative myogenesis., Sajedah M. Hindi 1986-
The role of stem cells in adipose tissue remodeling., Candice ReShay Holden 1988-
The impact of inflammatory and immune response-related genetic variants on prostate cancer risk among men of African descent., Dominique Zilpha Jones
A mechanism for trif adaptor-biased signaling by toll-like receptor 4., Joseph Peterson Kolb
Functional implications of demyelination and the molecular control of remyelination in the adult mouse., Nicholas John Kuypers
Extracellular matrix proteins and the liver-lung axis in disease., Veronica L. Massey
Development of models for the study of the molecular mechanisms of host restriction and adaptation of hantaviruses., Ryan Carroll McAllister 1988-
BDNF maintains adult taste innervation and is required for taste nerve regeneration after injury., Lingbin Meng
IL-12 induced modulation of tumor derived myeloid cell inflammatory responsiveness., Courtney Jetun Mitchell
Post-transcriptional regulation of the Type IIA sodium-phosphate cotransporter by parathyroid hormone., Rebecca Dale Murray
Epigenetic modifications associated with aortic remodeling in hyperhomocysteinemia., Nithya Narayanan
Myocyte-specific overexpression of stromal cell-derived Factor 1 facilitates cardiac regeneration and improves myocardial function after infarction in mice., Detlef Ernst-Rudolf Obal
Effects of step training on the kidneys following spinal cord injury in rats., Pradeepa Poudyal
Bone strength and architecture : pharmacological targeting of CaMKK2 as a method for enhancing bone quality., Zachary James Pritchard
Troglitazone suppresses glutamine metabolism and tumor cell growth through a ppar-independent mechanism., Miriam R. Reynolds 1965-
Modulation of the ovarian cancer humoral response by tumor-derived exosomes., Carolyn Denise Roberson
Genetic and mechanistic analysis of rat mammary cancer susceptibility., Jennifer Sanders
The anti-obesogenic effects of nitric oxide., Brian Edward Sansbury 1985-
Craniodental anatomy of a new late cretaceous multituberculate mammal from Udan Sayr, Mongolia., Amir Subhash Sheth
Lunasin reduces the melanoma stem cell population in vitro and inhibits tumor proliferation in vivo., Christopher Paul Shidal
Preventive effect of non-mitogenic acidic fibroblast growth factor on diabetes-induced testicular cell death., Melissa Skibba 1990-
Building a metabolic bridge between glycolysis and sphingolipid biosynthesis : implications in cancer., Morgan L. Stathem
Inducible tumor difference between rapid and slow rat Nat2 congenic Fischer 344 rats administered methyl-nitrosourea., Marcus W. Stepp
Effects of passive immobilization on locomotor recovery after spinal cord injury in adult rats., Kelsey Lee Stipp
Evaluating the effects of aroclor 1260 in non-alcoholic fatty liver disease : the role of xenobiotic receptors., Banrida Wahlang
Mechanisms of action and co-optive evolution for hypervariable courtship pheromones in plethodontid salamanders., Wilburn Beau Wilburn
Inflammation-resolving lipid mediators promote revascularization to enhance wound healing., Michael Jingyuan Zhang
Regulation of macrophage inflammatory signaling pathways by AMP-activated protein kinase., Yanfang Zhu
Theses/Dissertations from 2013
Probing the anti-cancer mechanism of selenite : a metabolic approach., Alex Belshoff
Mast cell-T cell interactions in inflammatory chemokine mediated immune surveillance of intestinal cancer., Sobha R. Bodduluri
AMP-activated protein kinase regulation of myeloid antigen presenting cell activity., Kelly Casey Carroll
Cyclin E induction and oncolytic replication of E1b-deleted adenoviruses., Pei-Hsin Cheng
Genetic mapping and mechanism of action of rat mammary carcinoma susceptibility quantitative trait locus Mcs1b., Aaron D. denDekker
Role of ethanol as a cofactor in HAART induced hepatic steatosis and injury., Hridgandh Donde
Enhanced penetration of lipid functionalized nanoparticles in 3D cell cultures., Christopher Gene England 1988-
Synapses, spines, zinc and pathology of Alzheimer's disease., Dmitry Familtsev 1985-
The role of neurotrophin receptors in taste development., Da Fei
The retina-prosthesis interface in two rat models of retinitis pigmentosa and functional changes associated with photoreceptor loss., James William Fransen
Effects of telemetry EMG implants on hindlimb locomotor recovery in thoracic spinal contused rats., Matthew L. Hamilton
Molecular bases of inherited bone marrow failures : Shwachman-Diamond syndrome and Diamond Blackfan anemia., Adrianna Lee Henson 1983-
Gene expression analysis of neurotrophins, Trk receptors, and associated regulatory molecules after contusive spinal cord injury., Matthew Tyler Hougland 1982-
Post-mortem analysis of cortical thickness and neuronal morphometry in autism., Shweta Sunil Kamat
Audiovisual sensory processing in autism spectrum condition., Ryan Mikel Burdette Kiser
6-phosphofructo-2-kinase inhibition induces autophagy as a survival mechanism., Alden Klarer
Preclinical safety assessment of Griffithsin-based vaginal microbicides., Amanda Lasnik
COUP-TFII and its interacting proteins in breast cancer and endocrine resistance., Lacey Morgan Litchfield
Using the virtual world of Second Life to teach cultural competence for health science professional students., Ashley Mack 1986-
Constructing the rod bipolar cell signalplex using animal models of retinal dysfunction., Thomas Andrew Ray 1986-
Olanzapine-induced liver injury : direct metabolic effects, exacerbation by high-fat diet, and protection with sulforaphane., Robin H. Schmidt 1984-
The role of a7 nicotine acetylcholine receptors in lung injury and repair., Glenn Vicary
PACAP : a novel neuropeptide for pituitary gonadotroph maturation, function and regulation., Rongqiang Yang
The involvement of beta-catenin in the inflammatory response leading to autoimmune diabetes development., Arin Lee Zirnheld
Theses/Dissertations from 2012
Approaches in the treatment of Parkinson's disease : a focus on stem cell-based therapies., Tareq Al-maqtari 1979-
Acetaldehyde dehydrogenase 2 (ALDH2) activation protects hepatocytes from mitochondrial damage and death caused by 4-hydroxynonenal., Keegan J. Baldauf 1982-
Pivotal role of Interleukin-10 on microRNA-155 expression in regulation of the monocyte response in hypothermia., Adrian Theophil Billeter 1984-
The dynamic equilibrium of human telomeric G-quadruplexes., Robert Buscaglia
Gain and loss of functional locomotor recovery following contusive spinal cord injury in the adult rat., Krista Layne Caudle
The role of endogenous Bcl-xL in regulation of apoptotic signaling pathways., Colins Ogwandi Eno 1982-
Idiopathic pulmonary fibrosis : diagnosis, management, and the search for a cure., Daniel Fioret
Development of pituitary tumor-transforming gene (PTTG) transgenic mice for the treatment of ovarian cancer., Miranda Y. Fong 1982-
Role of human arylamine N-acetyltransferase in carcinogen metabolism and human breast cancer progression., Carmine Simone Leggett
Co-option and adaptation of novel gene duplications for pheromone activity in a dusky salamander., Kari Anne Leichty 1987-
Dysregulation of microRNA expression in acquired endocrine-resistant breast cancer., Tissa Thomas Manavalan
Integrin inhibitor cycloRGDfV blunts enhanced LPS-induced liver injury caused by ethanol in mice., Veronica L. Massey
Blockade of CXCR4 inhibits Porphyromonas gingivalis colonization in vivo and subsequent periodontal bone loss., Megan L. Mc Intosh
Regulation of vascular smooth muscle cell phenotype., Joshua Kuimeta Salabei
The regulation of RNA Polymerase I-mediated transcription in forebrain neurons., Scott Carl Smith
Hyperhomocysteinemia alters sinoatrial and atrioventricular nodal function : role of the cardiac NMDA receptor., Chirag V. Soni
Expression of adipocyte/macrophage fatty acid binding protein promotes tumor growth and metastasis., Ashley Simone Triplett
