This collection includes theses and dissertations from the School of Medicine. It is not exhaustive since most paper theses and dissertations have not been digitized. Generally, paper copies of theses and dissertations published prior to 2014 can be accessed in the University of Louisville Libraries. If you would like to add your thesis or dissertation to this collection, please see: http://ir.library.louisville.edu/about.html.

Follow

Theses/Dissertations from 2018

PDF

Nutritional virulence of Legionella pneumophila., Ashley M. Best

PDF

Functional and structural impact of the loss of the leucine-rich repeat protein LRIT1 in the mouse retina., Catherine Ann Cobb

PDF

Maturation of human induced pluripotent stem cell derived engineered cardiac tissues using chief transfection and chronic optical pacing., Marc M. Dwenger

PDF

Traumatic brain injury : investigating misconceptions among graduate students in physical therapy, occupational therapy, and speech-language pathology., Michael Frazure

PDF

Inflammasome independent leukotriene-b4 production drives crystalline silica induced sterile inflammation., Bindu Hegde

PDF

Autism spectrum disorder : investigating predictive diagnostic relationships in children three years-of-age and younger., Kaitlin Juergensen

PDF

Swallow and breathing coordination following suprahyoid muscle injury., Bradley Kimbel

PDF

Vinyl chloride enhances diet-induced liver injury via metabolic dyshomeostasis : critical role of mitochondria., Anna L. Lang

PDF

A study of GPR3, GPR6, of GPR12 as novel molecular targets for cannabidiol., Alyssa S. Laun

PDF

A new surgical approach for O-C2 fusion, solving the problem of dysphagia., M. Kathryn McClure

PDF

Divergent evolution of di-lysine ER retention vs. farnesylation motif-mediated anchoring of the ankb virulence effector., John David Perpich

PDF

Therapeutic potential of a plant-made cholera toxin b subunit variant for the treatment of ulcerative colitis., Joshua Mark Royal

PDF

Characterization of type II toxin anti-toxin systems in Aggregatibacter actinomycetemcomitans., Blair W. Schneider

PDF

Feeding behaviors and the child with posterior tongue-tie : comparison to norms., McKenzie Sexton

PDF

The effects of polychlorinated biphenyls exposure on non-alcoholic fatty liver disease : role of aryl hydrocarbon receptor., Hongxue Shi

PDF

Exercise preconditioning and TFAM overexpression diminish skeletal muscle atrophy., Nicholas Todd Theilen

PDF

Characterizing the virulence factor YapE in Yersinia pestis., Tiva Templeton VanCleave

PDF

The involvement of epithelial cells in arenavirus-induced pathogenesis., Nikole Leslie Margaret Warner

PDF

A model to study the effects of whole life chronic exposure to arsenic or cadmium on the development of adult metabolic syndrome : initial characterization of hepatic changes., Jamie L. Young

PDF

Tissue engineered micro and macrovasculature utilizing stromal vascular fraction., Joseph Samir Zakhari

Theses/Dissertations from 2017

PDF

MiRNA expression changes in arsenic-induced skin cancer in vitro and in vivo., Laila Al-Eryani

PDF

Characterization of Filifactor alocis and its immune evasion strategies employed against human neutrophils., Cortney Linn Armstrong

PDF

Enhancing cell therapy for ischemic cardiomyopathy., Michael J. Book

PDF

Neural coding of natural and synthetic speech., Allison Brown

PDF

PCB-associated steatohepatitis and the role of nuclear receptors., Heather Brooke Clair

PDF

Spinal cord injury induced cardiac decline and the limitations of exercise., Kathryn Michele DeVeau

PDF

Spontaneous vocal matching in mothers and their hearing impaired infants with cochlear implants : a quantitative analysis., Lydia Doggett

PDF

The effects of moderate alcohol consumption and inflammation on the hepatic matrisome and the renal cortex proteome., Christine E. Dolin

PDF

Metabolic regulation of myocardial adaptation to exercise., Andrew Alan Gibb

PDF

Age-related host factors regulate lung cancer progression., John Caleb Greenwell

PDF

Targeting the glucose metabolism of myeloid-derived suppressor cells (MDSCs) to stimulate cancer immunity., Jaspreet Grewal

PDF

Targeting the major regulator of mitosis., J. Mason Hoffman

PDF

Diffusion-weighted magnetic resonance imaging in diagnosing graft dysfunction : a non-invasive alternative to renal biopsy., Elizabeth Marie Hollis

PDF

Identifying the signaling mechanisms of EGFR-mediated apoptosis., Nicole Marion Jackson

PDF

Advances in tumor-targeted therapy using nanomedicine., Divya Karukonda

PDF

Stretching adversely modulates locomotor capacity following spinal cord injury via activation of nociceptive afferents., Anastasia V. Keller

PDF

Mitochondrial Transcription Factor A's role in heart failure., George H. Kunkel

PDF

UBQLN1 : a multi-domain protein with multiple functions., Zimple Kurlawala

PDF

Withaferin a synergistically enhances the effects of paclitaxel against lung cancer., Al Hassan Kyakulaga

PDF

Prevention and treatment of familial adenomatous polyposis and colorectal cancer by bilberry-derived anthocyanidins., Ashley M. Mudd

PDF

Role of MIR-29B-1 and MIR-29A in endocrine-resistant breast cancer., Penn Muluhngwi

PDF

The interaction of homoserine lactones and paraoxonase 2 modulates cell death signaling and cell proliferation., Aaron Mackallan Neely

PDF

Reversible silencing of spinal neurons unmasks a left-right coordination continuum., Amanda Marie Pocratsky

PDF

Novel insight into the liver-lung axis in alcohol-enhanced acute lung injury., Lauren G. Poole

PDF

The DLK1-MEG3 locus in malignant cells of proposed primordial germ cell origins., Zachariah Payne Sellers

PDF

Revisiting neutrophil responses to toll-like receptor 4 : influence of ligand structures and cellular environments., Shuvasree Sengupta

PDF

The role of HIF-1α in intestinal epithelial barrier function in alcoholic liver disease., Tuo Shao

PDF

Combating malignant melanoma with the multifaceted soy-dervied peptide lunasin., Christopher Paul Shidal

PDF

Trunk and respiratory motor control in typically developing children and its implications in children with chronic spinal cord injury., Goutam Singh

PDF

The comparative cytotoxicity and genotoxicity of hexavalent chromium in humans and sea turtles., Rachel M. Speer

PDF

Role of human arylamine n-acetyltransferase 1 in tumorigenesis and cancer biology., Marcus William Stepp

PDF

BDNF-TRKB signaling regulates adult taste bud innervation., Tao Tang

PDF

Characterization of a mutant oncolytic adenovirus and the role of jnk in enhancing virotherapy., Stephen L. Wechman

PDF

Targeting Fas pathway as an effective means of inducing tolerance to pancreatic islets., Kyle Blake Woodward

PDF

Circuits for active vision : parallel tectothalamocortical visual pathways in the mouse., Na Zhou

Theses/Dissertations from 2016

PDF

Cardiovascular and hematopoietic responses to volatile benzene exposure., Wesley Tyler Abplanalp

PDF

Identification of residual descending pathways after human spinal cord injury., Darryn A. Atkinson

PDF

Role of phosphodiesterase-4 in alcohol-induced organ injury., Diana Veronica Avila

PDF

Immune monitoring in recipients of combined living donor kidney and hematopoietic stem/facilitating cell transplants., Mark DeWayne Badder

PDF

SA-4-1BBL as a modulator of innate, adaptive, and regulatory immunity : implications for cancer prevention and treatment., Hampartsoum Barsoumian

PDF

Establishing a clinically relevant mouse model of human AML to test novel transmethylation inhibitors., Aditya Barve

PDF

Carnosine, a therapeutic potential for critical limb ischemic., Adjoa Agyemang Boakye

PDF

The role of the MiR-200 family on the tumor suppressor RASSF2 and the effect on MAPK pathway activity in colorectal cancer., Jane V. Carter

PDF

Acrolein is a critical mediator of alcohol-induced liver and intestinal injury in alcoholic liver disease., Wei-Yang (Jeremy) Chen 1980-

PDF

Identification of host factors required for Yersinia pestis macrophage intracellular survival and their impact on vacuole maturation, acidification and trafficking., Michael Graylin Connor

PDF

The role of O-GlcNAcase during heart failure., Sujith Dassanayaka

PDF

Impact of epigallocatechin-3-gallate (EGCG), a broad-spectrum anti-inflammatory, in controlling intestinal factors contributing to inflammatory bowel disease., Gerald Wayne Dryden, Jr.

PDF

Toll-like receptor 4 mutation suppresses hyperhomocysteinemia-mediated hypertension., Anastasia Familtseva

PDF

Air pollution, pulmonary oxidative stress, and the endothelin system in the development of cardiovascular injury., Jordan B. Finch

PDF

Microbiota activated CD103+ DCS stemming from oral microbiota adaptation specifically drive γδT17 proliferation and activation., Christopher Jay Fleming

PDF

In vivo monitoring of therapeutic efficacy and virulence profile by bioluminescent Klebsiella pneumoniae., Ramy Ameen Fodah

PDF

The role and regulation of inhibitor of Kappa B Kinase in the impaired monocyte response., Norman James Galbraith

PDF

Glutathione s-transferase p in glucose homeostasis in mice., Shubha Ghosh Dastidar

PDF

Isolation of EGFR-containing early endosomes., Julie A. Gosney

PDF

Characterization of the role of the Burkholderia pseudomallei type 3 secretion system using in vivo imaging., Maria Gabriela Gutierrez

PDF

The role of the nucleolus in neurodegeneration., Justin Lauren Hallgren

PDF

Role of microRNA-21 in atherogenesis., Rihab Hamed-Berair

PDF

Evaluating cardiovascular dysfunction during increased activity and exercise rehabilitation following incomplete thoracic spinal cord injury in the adult rat., Kathryn A. Harman

PDF

Pro-inflammatory cytokines promote viral replication and cell cycle mediators in arenavirus-induced hepatitis., Gretchen E. Holz

PDF

MicroRNA-186 and metastatic prostate cancer., Dominique Zilpha Jones

PDF

Cell-based therapies for ischemic cardiomyopathy : investigations of intramyocardial retention and safety of high dose intracoronary delivery of c-kit positive cardiac progenitor cells, and therapeutic utility of a novel population of cardiac mesenchymal stem cells expressing stage-specific embryonic antigen-3 (SSEA-3)., Matthew C. L. Keith

PDF

Molecular characterization of human papillomavirus in head and neck tumors., Sujita Khanal

PDF

Modulation of cardiac Kv currents by Kvbeta2 and pyridine nucleotides., Peter Joseph Kilfoil

PDF

ABIN1 in the pathogenesis of Glomerulonephritis and the novel polocyte-neutrophil proinflammatory axis., Erik Anderson Korte

PDF

Effects of neonatal capsaicin on formalin-induced ATF3 expression in the adult rat., Sarah Krupp

PDF

Vinyl chloride-diet interactions in liver disease : potential roles of autophagy and energy management., Anna L. Lang

PDF

Congenic and functional analysis of rat mammary cancer susceptibility., Saasha Le

PDF

TNF-like weak inducer of apoptosis (TWEAK) : not so weak after all., Joseph Dekward McMillan IV

PDF

A systems biology approach identifies a gene regulatory network in parotid acinar cell differentiation., Melissa Ann Metzler

PDF

Modulation of cell death signaling and cell proliferation by the interaction of homoserine lactones and Paraoxonase 2., Aaron Mackallan Neely

PDF

Transient receptor potential cation channel, subfamilies V, member 1 (TRPV1) and M, member 1 (TRPM1) contribute to neural signaling in mouse retina., Jennifer Noel

PDF

The influence of miR-99a on mTOR signaling regulation in colorectal cancer cell lines., Jonathan Rice

PDF

Developing a more clinically-relevant mouse model of cisplatin-induced nephrotoxicity., Cierra N. Sharp

PDF

The discovery of a novel, Ras-mediated NORE1A/PMLIV tumor suppressor complex., Jessica Mezzanotte Sharpe

PDF

Multipurpose tenofovir disoproxil fumarate electrospun fibers for the prevention of HIV-1 and HSV-2 infections., Kevin Tyo

PDF

The role of nicotine, a7 nicotinic acetylcholine receptors and extracellular matrix remodeling in pulmonary fibrosis., Glenn Ward Vicary

PDF

The effects of direct peritoneal resuscitation on leukocyte infiltration after acute brain death., Jessica Lee Weaver

Theses/Dissertations from 2015

PDF

Immunomodulation of myeloid-derived suppressor cells by particulate b-glucan in cancer., Sabrin Husein Albeituni

PDF

Characterizing the neuropeptide pathways between the forebrain and the pons., Ali Al-Magableh

PDF

Promoting differentiation and survival of human c-kit+ cardiac progenitor cells ex vivo., Tareq Al-Maqtari